Journal
FITOTERAPIA
Volume 86, Issue -, Pages 183-187Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.fitote.2013.03.010
Keywords
Pogostemon cablin; Sesquiterpene; Patchoulene; Guaiane; Hepatoprotective activity
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Funding
- National Natural Science Foundation of China [21132009]
- National Science and Technology Project of China [2011ZX09307-002-01]
- National Basic Research Program of China [2009CB523004]
- Program for Changjiang Scholars and Innovative Research Team in University of Ministry of Education of China [IRT1007]
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Four new sesquiterpenes (1-4), together with four known compounds (5-8), were isolated from the stems of Pogostemon cablin (Blanco.) Benth. Their chemical structures were elucidated by means of spectroscopic methods, including 1D and 2D NMR, HRESIMS, IR, and UV. Hepatoprotective activities of these compounds were investigated, by studying the protective effect on HL-7702 cellular injury induced by DL-galactosamine. (C) 2013 Elsevier B.V. All rights reserved.
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