Journal
FITOTERAPIA
Volume 83, Issue 4, Pages 665-670Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.fitote.2012.02.003
Keywords
Epimedium elatum; Acylated flavonol glycosides; Elatoside A; Elatoside B; Antimicrobial; PPAR-gamma
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Funding
- University of Mississippi, United States
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Herba Epimedii is a well-known Botanical preparation used over long time in traditional Chinese medicine. The extracts and chemical constituents from Epimedium species are aphrodisiac as well as to treat many ailments. Chemical investigation of lonely species growing in Kashmir Himalaya Epimedium elatum was undertaken to evaluate its chemical profile. Two unusual substituted acylated flavonol glycosides named Elatoside A (1) and Elatoside B (2) have been isolated from the ethanolic extract of E. elatum along with 23 previously known ones (3-25). All isolates were evaluated for antimicrobial and PPAR-gamma ligand binding activity, and some of them appeared to be modestly active. Published by Elsevier B.V.
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