Journal
FITOTERAPIA
Volume 83, Issue 3, Pages 563-567Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.fitote.2011.12.027
Keywords
Gardenia jasminoides Ellis; Lignan glucoside; Iridoid glucoside; Short-term-memory enhancement
Categories
Funding
- National Natural Science Foundation of PR China [30701047]
- Ministry of Education of China [NCET-10-0120]
- Fundamental Research Funds for the Central Universities [21611203]
- China Postdoctoral Science Foundation [20110490916]
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A new lignan glucoside, (+)-(7S,8R,8'R)-lyoniresinol 9-O-beta-D-(6 ''-O-trans-sinapoyl)glucopyranoside (1), and a new iridoid glucoside, 10-O-trans-sinapoylgeniposide (2), together with eight known compounds, were isolated from the fruits of Gardenia jasminoides Ellis. The structures of the isolates were elucidated by extensive spectroscopic studies, including UV, IR, 1D and 2D NMR, ESI-MS, HR-ESI-MS, and CD experiments. The short-term-memory-enhancement activities of some compounds were evaluated on an A beta transgenic drosophila model. (C) 2012 Elsevier B.V. All rights reserved.
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