4.6 Article

Chemical constituents of the aerial part of Derris elliptica

Journal

FITOTERAPIA
Volume 83, Issue 4, Pages 732-736

Publisher

ELSEVIER SCIENCE BV
DOI: 10.1016/j.fitote.2012.02.015

Keywords

Coumaronochromone; Favonoids; Insecticidal activities; Cytotoxicity; Derris elliptica

Funding

  1. National Department Public Benefit Research Foundation of China [200903052]

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A new coumaronochromone,6,4'-dihydroxy-7,5'-dimethoxy-coumaronochromone (1), together with eleven known flavonoids (2-12) were isolated from the ethanol extract of the aerial part of Derris elliptica. Their structures were elucidated on the basis of spectroscopic analysis. Compounds 2, 4, 7,8 and 9 exhibited moderate insecticidal activities against larvae of Aedes albopictus. All compounds showed strong cytotoxic activities against Spodoptera litura (SL) and Trichoplusia ni BTI-Tn-5B1-4 (Hi-5) cells comparison to positive control of rotenone. (C) 2012 Elsevier B.V. All rights reserved.

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