Journal
FITOTERAPIA
Volume 83, Issue 7, Pages 1191-1195Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.fitote.2012.07.001
Keywords
Laurencia composita; Sesquiterpene; Chamigrane; Eudesmane
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Funding
- National Natural Science Foundation of China [41106136, 41106137]
- Shandong Province Natural Science Foundation [ZR2009BQ021]
- Chinese Academy of Sciences for Key Topics in Innovation Engineering [KZCX2-YW-QN209]
- Foundation of the Chinese Academy of Sciences for President's Scholarship
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Four new chamigrane derivatives, laurecomin A (1). laurecomin B (2), laurecomin C (3), and laurecomin D (4), one new naturally occurring sesquiterpene, 2,10-dibromo-3-chloro-7-chamigren-9-ol acetate (5), and three known halogenated structures, deoxyprepacifenol (6), 1-bromoselin-4(14),11-diene (7), and 9-bromoselin-4(14).11-diene (8), were isolated from the marine red alga Laurencia cornposita collected from Pingtan Island, China. The structures of these compounds were unambiguously established by 1D, 2D NMR and mass spectroscopic techniques. The bioassay results showed that 2 was active against both brine shrimp and fungus Colletotrichum lagenarium. (C) 2012 Elsevier B.V. All rights reserved.
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