Journal
FITOTERAPIA
Volume 83, Issue 2, Pages 323-328Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.fitote.2011.11.010
Keywords
Tupistra chinesis; Steroidal saponin; Furostanol; Diastereoisomer; Cytotoxicity
Categories
Funding
- National Natural Science Foundations of China [30870254, 31070313, 30670213]
- Natural Science Foundation of Hubei Province [2007ABC008]
Ask authors/readers for more resources
Five new furostanol saponins (1-5), together with three known compounds (6-8) were obtained from the n-butanol soluble fraction of ethanol extract from Tupistra chinensis. Their structures were determined on the basis of chemical methods and spectral data. The isolated compounds were tested in vitro for their cytotoxic activities against the A549, HepG 2 and Caski cancer cell lines. Among them, compounds 6, 7, and 8 showed cytotoxicity against A549 cancer cell lines with IC50 values of 6.6, 6.7 and 29.1 mu M, respectively. (C) 2011 Elsevier B.V. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
