Journal
FITOTERAPIA
Volume 81, Issue 7, Pages 878-883Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.fitote.2010.05.016
Keywords
Eucalyptus loxophleba; Sideroxylonals; Loxophlebal A; Large scale isolation; Antibacterial
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Funding
- NIPER
- Australian Government, Rural Industries Research and Development Corporation
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Loxophlebal A, a new antibacterial formylated phloroglucinol was isolated from the mother liquor obtained after separation of sideroxylonals from the chloroform-methanol extract of leaves of Eucalyptus loxophleba ssp lissophloia. The structure of loxophlebal A was determined to be 3-desformyl sideroxylonal A by spectroscopic methods including 1D- and 2D-NMR. The stereochemistry of loxophlebal A was determined by chemical correlation with sideroxylonal A. This article also reports an efficient, simple and economic method for large scale isolation of sideroxylonals in a purity of >90% from the leaves of Eucalyptus loxophleba ssp lissophloia. (C) 2010 Elsevier B.V. All rights reserved.
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