Journal
FITOTERAPIA
Volume 81, Issue 1, Pages 45-49Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.fitote.2009.07.004
Keywords
Dysophylla stellato; Anti-inflammatory; Cyclooxygenase (COX)-1; COX-2; Antioxidant; Stellatin
Categories
Funding
- NIPER
Ask authors/readers for more resources
The n-hexane and ethyl acetate extracts of whole plants of Dysophylla stellata significantly inhibited edema when applied topically at doses of 0.5 and 1 mg/ear in TPA-induced ear edema assay in mice. Further, both the extracts were evaluated for COX-1 and COX-2 inhibitory activities and showed 85.42 and 57.38%; and 71.79 and 89.27% inhibition at 50 mu g/ml, respectively. Chromones (1 and 2) present in these extracts could be responsible for their COX-1 and COX-2 inhibitory and anti-inflammatory activities. The ethyl acetate extract showed antioxidant activity in DPPH and ABTS radical scavenging assay where as n-hexane extract found to be inactive. (C) 2009 Elsevier B.V. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available