Journal
FITOTERAPIA
Volume 80, Issue 8, Pages 496-505Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.fitote.2009.06.012
Keywords
Ashwagandha; Genetic diversity; Isoenzymes; RAPD; Withanolide diversity; Withania somnifera
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Funding
- New Millennium Initiative on Technology & Leadership in India (NMITLI-India)
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Withania somnifera is one of the most important medicinal plants of Ayurveda and finds extensive uses in Indian traditional herbal preparations. In this investigation, selected accessions of the plant were examined for diversity through RAPDs, isoenzymes, polypeptide polymorphism and withanolide profiles. The accessions clustered together with respect to their characteristic profile of major withanolides and represented withaferin A, withanone, withanolide D or withanolide A rich groups. This level of phytochemical diversity as discrete chemotypes is widest and is being first ever documented to occur in Indian population of the plant. (C) 2009 Elsevier B.V. All rights reserved.
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