Journal
FITOTERAPIA
Volume 80, Issue 3, Pages 182-187Publisher
ELSEVIER
DOI: 10.1016/j.fitote.2009.01.007
Keywords
Cordyceps sinensis; Polysaccharide; Macrophage; TNF-alpha
Categories
Ask authors/readers for more resources
It has been reported that mycelia of the Cordyceps sinensis (CS) can function as an immunostimulant. However, the active constituents of the mycelia are not well known. In this study, we investigated which components of the mycelia of CS induce monocyte activation and then structurally analyzed the active components. Assay of the effect of crude-(CS-P), soluble-(CS-Ps) and insoluble-(CS-Pp), polysaccharides extracted from the mycelia of CS, on macrophage production of TNF-alpha, indicated that CS-Pp enhanced TNF-alpha production to the highest extent. Furthermore, Structural analyses demonstrated that CS-Pp is a 1,3-beta-D-glucan contained some 1,6-branched chains and the mean particle diameter is 1.5 mu m. (C) 2009 Elsevier B.V. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available