Antibacterial triterpenes from the threatened wood-decay fungus Fomitopsis rosea

From a biologically active extract from the fungus Fomitopsis rosea, two new lanostane triterpenes were isolated, 3 alpha-(3'-butylcarboxyacetoxy)oxepanoquercinic acid C 1 and 3 alpha-hydroxy-24-methylene-23-oxolanost-8-en-26-carboxylic acid 2, along with three known triterpenes, 3-5, and the epidioxy sterol derivative 6. The structures of the compounds were elucidated based on their spectral properties. All triterpenes demonstrated antibacterial activity against S. aureus but possessed no antiradical activity against DPPH radicals. (C) 2009 Elsevier B.V. All rights reserved.