Journal
FITOTERAPIA
Volume 79, Issue 3, Pages 174-178Publisher
ELSEVIER
DOI: 10.1016/j.fitote.2007.11.007
Keywords
ginger; ethanol; antioxidant enzymes; lipid peroxidation; hepatic tissue; reactive oxygen species
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The current investigation has been conducted to investigate the influence of ginger on hepatic antioxidant enzymes system in ethanol treated rats. Ethanol significantly decreased the superoxide dismutase, catalase, glutathione peroxidase, glutathione reductase and glutathione content while an increase of malondialdehyde (MDA) levels were estimated in the hepatic tissue. This effect was reversed by a treatment with 1% dietary ginger for 4 weeks in rats by improved antioxidant status which suggest that treatment of ginger may have protective role against the ethanol induced hepatotoxicity. (C) 2007 Elsevier B.V. All rights reserved.
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