Journal
FERTILITY AND STERILITY
Volume 95, Issue 8, Pages 2631-2633Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.fertnstert.2011.01.141
Keywords
Blastocyst; secretome; noninvasive; aneuploidy screening
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This study has identified the first protein, lipocalin-1, in the secretome of human blastocysts that is associated with chromosome aneuploidy. The development of a noninvasive technique to determine an embryo's developmental competence, including chromosomal constitution, by analysis of spent IVF culture medium will be a powerful tool for embryo selection in assisted reproductive technologies. (Fertil Steril (R) 2011;95:2631-3. (C) 2011 by American Society for Reproductive Medicine.)
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