4.7 Editorial Material

Involvement of anticentromere antibody in interference with oocyte meiosis and embryo cleavage

Journal

FERTILITY AND STERILITY
Volume 95, Issue 8, Pages 2729-2731

Publisher

ELSEVIER SCIENCE INC
DOI: 10.1016/j.fertnstert.2011.01.013

Keywords

Antinuclear antibody; anticentromere antibody; intracytoplasmic sperm injection

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The aim of this study was to investigate the clinical significance of anticentromere antibody (ACA) among types of antinuclear antibody (ANA) in the properties of oocytes retrieved from infertile women. The rate of metaphase II oocytes or embryo cleavage was significantly decreased in patients with positive ACA compared with patients with negative ACA, suggesting that ACA is an essential marker for flawed oocytes in infertile women with any type of ANA. (Fertil Steril (R) 2011;95:2729-31. (C)2011 by American Society for Reproductive Medicine.)

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