Journal
FERTILITY AND STERILITY
Volume 94, Issue 5, Pages 1915-1917Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.fertnstert.2009.12.082
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It is assumed somatic cells can die in the apoptotic, the autophagic, or the necrotic way; however, the mechanisms of sperm death are not clear. Here, ejaculated human spermatozoa were evaluated for apoptosis and reactive oxygen species production in the absence or presence of melatonin, and we concluded that melatonin reverses sperm apoptosis due to its free radical scavenging actions. (Fertil Steril (R) 2010;94:1915-7. (C) 2010 by American Society for Reproductive Medicine.)
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