Journal
FERTILITY AND STERILITY
Volume 93, Issue 1, Pages 301-303Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.fertnstert.2009.06.031
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The objective of this retrospective cohort study was to assess the potential effects of preconceptional short-term exposure to particulate air pollution in a real-world situation on pregnancy outcome in infertile women evaluating the possible role of IVF/embryo transfer treatment on this outcome using women who had conceived naturally for the first time during the same time frame as a matched control group. The study provides evidence for an association between brief exposure to high levels of ambient particulate matter (aerodynamic diameter <= 10 mu m) during the preconceptional period and early pregnancy loss, regardless of the method of conception, and showed a 2.6-fold increase in risk of miscarriage, suggesting a threshold instead of a monotonic effect of this exposure on reproductive outcome. (Fertil Steril(R) 2010;93:301-3. (C)2010 by American Society for Reproductive Medicine.)
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