Journal
FERTILITY AND STERILITY
Volume 91, Issue 4, Pages 1307-1310Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.fertnstert.2008.01.078
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Sperm analysis following World Health Organization guidelines is unable to explain the molecular causes of male infertility when basic sperm parameters are within a normal range and women do not present gynecologic pathology. Consequently, there is a need for accurate diagnostic tools in this area, and microarray technology emerges as promising. We present, for the first time, preliminary results of a comparison of sperm mRNA expression profiles between fertile and infertile men with normal semen parameters, discovering profound discrepancies between groups, with potential diagnostic and therapeutic possibilities. (Fertil Steril (R) 2009; 91:1307-10. (C)2009 by American Society for Reproductive Medicine.)
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