Letrozole versus clomiphene citrate: which is better for ovulation induction?

Letrozole is at least as effective as clomiphene for inducing ovulation and achieving pregnancy in patients with polycystic ovarian syndrome. Potential advantages of letrozole include reduced multiple pregnancies, absence of anti-estrogenic adverse effects, and the subsequent need for less intensive monitoring. (Fertil Steril (R) 2009;92:858-9. (C)2009 by American Society for Reproductive Medicine.)