4.7 Article

Assessment of ovarian function with anti-Mullerian hormone in systemic lupus erythematosus patients undergoing hematopoietic stem cell transplant

Journal

FERTILITY AND STERILITY
Volume 91, Issue 4, Pages 1529-1532

Publisher

ELSEVIER SCIENCE INC
DOI: 10.1016/j.fertnstert.2008.08.123

Keywords

Stem cell transplant; ovarian reserve; anti-Mullerian hormone

Funding

  1. National Institute of Child Health and Human Development
  2. National Cancer Institute
  3. National Institute of Dental and Craniofacial Research, NIH

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In this small pilot study, anti-Mullerian hormone (AMH) levels in women undergoing chemotherapy and hematopoietic stem cell transplantation facilitated earlier identification of impaired ovarian reserve compared with FSH and the resumption of menses. Larger studies are needed to accurately assess the clinical significance of AMH levels in the prediction of long-term reproductive outcomes in reproductive-age transplant patients with our current conditioning regimen. (Fertil Steril (R) 2009;91:1529-32. (C)2009 by American Society for Reproductive Medicine.)

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