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Dioxin may promote inflammation-related development of endometriosis

Journal

FERTILITY AND STERILITY
Volume 89, Issue -, Pages 1287-1298

Publisher

ELSEVIER SCIENCE INC
DOI: 10.1016/j.fertnstert.2008.02.102

Keywords

endometriosis; dioxin; progesterone; inflammation; leukocytes

Funding

  1. NICHD NIH HHS [K12HD043483, K12 HD043483, K12 HD043483-05] Funding Source: Medline
  2. NIEHS NIH HHS [R21 ES012298-01, R21 ES12298, R21 ES012298, R01 ES014942-01, R01 ES014942] Funding Source: Medline

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Laboratory and population-based studies suggest that exposure to environmental toxicants may be one of several triggers for the development of endometriosis. We discuss evidence that modulation of the endometrial endocrine-immune interface could mechanistically link toxicant exposure to the development of this disease.

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