Journal
FEMS MICROBIOLOGY LETTERS
Volume 357, Issue 1, Pages 63-68Publisher
OXFORD UNIV PRESS
DOI: 10.1111/1574-6968.12489
Keywords
antimicrobial peptide; database; antimicrobial activity; haemolytic/cytotoxic activity
Categories
Funding
- Shota Rustaveli National Science Foundation (Georgia)
- Centre National de la Recherche Scientifique (France) [09/10]
- ISTC-BTEP [G-2102]
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The Database of Antimicrobial Activity and Structure of Peptides (DBAASP) is a manually curated database for those peptides for which antimicrobial activity against particular targets has been evaluated experimentally. The database is a depository of complete information on: the chemical structure of peptides; target species; target object of cell; peptide antimicrobial/haemolytic/cytotoxic activities; and experimental conditions at which activities were estimated. The DBAASP search page allows the user to search peptides according to their structural characteristics, complexity type (monomer, dimer and two-peptide), source, synthesis type (ribosomal, nonribosomal and synthetic) and target species. The database prediction algorithm provides a tool for rational design of new antimicrobial peptides. DBAASP is accessible at http://www.biomedicine.org.ge/dbaasp/.
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