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Gene expression control by selective RNA processing and stabilization in bacteria

Journal

FEMS MICROBIOLOGY LETTERS
Volume 344, Issue 2, Pages 104-113

Publisher

OXFORD UNIV PRESS
DOI: 10.1111/1574-6968.12162

Keywords

RNA maturation; RNA degradation; RNA stability; RNase; translation; post-transcriptional regulation

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Funding

  1. Agence Nationale pour la Recherche [ANR-12-BSV6-0008-ReadRNA]
  2. CNRS
  3. INRA
  4. Agence Nationale de la Recherche (ANR) [ANR-12-BSV6-0008] Funding Source: Agence Nationale de la Recherche (ANR)

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RNA maturation is a key event regulating genes at post-transcriptional level. In bacteria, it is employed to adjust the amounts of proteins and functional RNAs, often in response to environmental constraints. During the process of RNA maturation, enzymes and factors that would otherwise promote RNA degradation convert a labile RNA into a stable and biologically functional molecule.

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