4.3 Article

RAPD: a database of recombinantly-produced antimicrobial peptides

Journal

FEMS MICROBIOLOGY LETTERS
Volume 289, Issue 2, Pages 126-129

Publisher

OXFORD UNIV PRESS
DOI: 10.1111/j.1574-6968.2008.01357.x

Keywords

antimicrobial peptides; chemical cleavage; database; enzymatic cleavage; fusion expression; recombinant approaches

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We have developed the Recombinantly-produced Antimicrobial Peptides Database (RAPD) to house relevant information on recombinant approaches to generate antimicrobial peptides. Key information stored in the database, which is extracted from published experiments, includes expression host, fusion strategy, release method and yield for individual peptides. Bibliographic data directly related to each particular case are also available. RAPD allows easy comparison of the relative popularity and efficiency of different strategies, and can thus be used as a guideline for future production of similar peptides. The database is freely available at http://faculty.ist.unomaha.edu/chen/rapd/index.php.

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