Journal
FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY
Volume 59, Issue 3, Pages 227-238Publisher
WILEY
DOI: 10.1111/j.1574-695X.2010.00665.x
Keywords
medical device; polymers; biofilm; bacterial infection; fungal infection; antibiotics
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Biofilms play a pivotal role in healthcare-associated infections, especially those related to the implant of medical devices, such as intravascular catheters, urinary catheters and orthopaedic implants. This paper reviews the most successful approaches for the control and prevention of these infections as well as promising perspectives for the development of novel devices refractory to microbial adhesion, colonization and biofilm formation.
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