Related references
Note: Only part of the references are listed.Canonical BMP7 activity is required for the generation of discrete neuronal populations in the dorsal spinal cord
Gwenvael Le Dreau et al.
DEVELOPMENT (2012)
Comprehensive analysis of TGF-β and BMP receptor interactomes
Mohammad Poorgholi Belverdi et al.
EUROPEAN JOURNAL OF CELL BIOLOGY (2012)
Growth differentiation factor 15 in cardiovascular diseases: from bench to bedside
Xinye Xu et al.
BIOMARKERS (2011)
Homomeric and heteromeric complexes among TGF-β and BMP receptors and their roles in signaling
Marcelo Ehrlich et al.
CELLULAR SIGNALLING (2011)
The TβR-I Pre-Helix Extension Is Structurally Ordered in the Unbound Form and Its Flanking Prolines Are Essential for Binding
Jorge E. Zuniga et al.
JOURNAL OF MOLECULAR BIOLOGY (2011)
The dynamic roles of TGF-beta in cancer
Erik Meulmeester et al.
JOURNAL OF PATHOLOGY (2011)
Latent TGF-β structure and activation
Minlong Shi et al.
NATURE (2011)
Myostatin Depletion: A Therapy for Ehlers-Danlos Syndrome?
Paolo Prontera et al.
ANNALS OF NEUROLOGY (2010)
Evidence for an early role for BMP4 signaling in thymus and parathyroid morphogenesis
Julie Gordon et al.
DEVELOPMENTAL BIOLOGY (2010)
Characterization of the Ligand Binding Functionality of the Extracellular Domain of Activin Receptor Type IIB
Dianne Sako et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
BMPR1a and BMPR1b Signaling Exert Opposing Effects on Gliosis after Spinal Cord Injury
Vibhu Sahni et al.
JOURNAL OF NEUROSCIENCE (2010)
BMP-2/6 Heterodimer Is More Effective than BMP-2 or BMP-6 Homodimers as Inductor of Differentiation of Human Embryonic Stem Cells
Elvira Valera et al.
PLOS ONE (2010)
Receptor oligomerization and beyond: a case study in bone morphogenetic proteins
Kai Heinecke et al.
BMC BIOLOGY (2009)
Redundancy of myostatin and growth/differentiation factor 11 function
Alexandra C. McPherron et al.
BMC DEVELOPMENTAL BIOLOGY (2009)
Macrophage Inhibitory Cytokine-1: Possible Bridge Molecule of Inflammation and Prostate Cancer
Dev Karan et al.
CANCER RESEARCH (2009)
Signaling cross-talk between TGF-beta/BMP and other pathways
Xing Guo et al.
CELL RESEARCH (2009)
The brachydactylies: a molecular disease family
S. Mundlos
CLINICAL GENETICS (2009)
Intricacies of BMP receptor assembly
Joachim Nickel et al.
CYTOKINE & GROWTH FACTOR REVIEWS (2009)
The RGM/DRAGON family of BMP co-receptors
Elena Corradini et al.
CYTOKINE & GROWTH FACTOR REVIEWS (2009)
TGF-β3 and cancer: A review
H. G. Laverty et al.
CYTOKINE & GROWTH FACTOR REVIEWS (2009)
The structure of myostatin: follistatin 288: insights into receptor utilization and heparin binding
Jennifer N. Cash et al.
EMBO JOURNAL (2009)
Crystal structure analysis reveals a spring-loaded latch as molecular mechanism for GDF-5-type I receptor specificity
Alexander Kotzsch et al.
EMBO JOURNAL (2009)
Lack of the bone morphogenetic protein BMP6 induces massive iron overload
Delphine Meynard et al.
NATURE GENETICS (2009)
The Solution Structure of BMPR-IA Reveals a Local Disorder-to-Order Transition upon BMP-2 Binding
Jochen Klages et al.
BIOCHEMISTRY (2008)
Elucidation of the role of activin in ovganogenesis using a multiple organ induction system with amphibian and mouse undifferentiated cells in vitro
Makoto Asashima et al.
DEVELOPMENT GROWTH & DIFFERENTIATION (2008)
Crystal structure analysis reveals how the chordin family member crossveinless 2 blocks BMP-2 receptor binding
Jin-li Zhang et al.
DEVELOPMENTAL CELL (2008)
Identification of a novel pool of extracellular pro-myostatin in skeletal muscle
Sarah B. Anderson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Targeting of bone morphogenetic protein growth factor complexes to fibrillin
Gerhard Sengle et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Characterization of ligand-binding properties of the human BMP type II receptor extracellular domain
Huiran Yin et al.
JOURNAL OF MOLECULAR BIOLOGY (2008)
Cooperative assembly of TGF-β superfamily signaling complexes is mediated by two disparate mechanisms and distinct modes of receptor binding
Jay Groppe et al.
MOLECULAR CELL (2008)
Type I receptor binding of bone morphogenetic protein 6 is dependent on N-glycosylation of the ligand
Stefan Saremba et al.
FEBS JOURNAL (2008)
BMP-3 and BMP-6 structures illuminate the nature of binding specificity with receptors
George P. Allendorph et al.
BIOCHEMISTRY (2007)
A silent H-bond can be mutationally activated for high-affinity interaction of BMP-2 and activin type IIB receptor
Dionys Weber et al.
BMC STRUCTURAL BIOLOGY (2007)
High resolution structures of the bone morphogenetic protein type II receptor in two crystal forms: Implications for ligand binding
Peter D. Mace et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
Genetic analysis of the roles of BMP2, BMP4, and BMP7 in limb patterning and skeletogenesis
Amitabha Bandyopadhyay et al.
PLOS GENETICS (2006)
Pituitary actions of ligands of the TGF-β family:: activins and inhibins
Louise M. Bilezikjian et al.
REPRODUCTION (2006)
TGF-β superfamily members and ovarian follicle development
Phil G. Knight et al.
REPRODUCTION (2006)
Structure of the ternary signaling complex of a TGF-β superfamily member
George P. Allendorph et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Role of macrophage inhibitory cytokine-1 in tumorigenesis and diagnosis of cancer
Asne R. Bauskin et al.
CANCER RESEARCH (2006)
Protein family expansions and biological complexity
Christine Vogel et al.
PLOS COMPUTATIONAL BIOLOGY (2006)
A modular interface of IL-4 allows for scalable affinity without affecting specificity for the IL-4 receptor
Michael Kraich et al.
BMC BIOLOGY (2006)
Structural basis for the inhibition of activin signalling by follistatin
AE Harrington et al.
EMBO JOURNAL (2006)
Three key residues underlie the differential affinity of the TGFβ isoforms for the TGFβ type II receptor
G De Crescenzo et al.
JOURNAL OF MOLECULAR BIOLOGY (2006)
The structure of the Follistatin:Activin complex reveals antagonism of both type I and type II receptor binding
TB Thompson et al.
DEVELOPMENTAL CELL (2005)
Activating and deactivating mutations in the receptor interaction site of GDF5 cause symphalangism or brachydactyly type A2
P Seemann et al.
JOURNAL OF CLINICAL INVESTIGATION (2005)
GDF11 forms a bone morphogenetic protein 1-activated latent complex that can modulate nerve growth factor-induced differentiation of PC12 cells
GX Ge et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
Crystal structure of BMP-9 and functional interactions with pro-region and receptors
MA Brown et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
A single residue of GDF-5 defines binding specificity to BMP receptor IB
J Nickel et al.
JOURNAL OF MOLECULAR BIOLOGY (2005)
Biophysical comparison of BMP-2, ProBMP-2, and the free pro-peptide reveals stabilization of the pro-peptide by the mature growth factor
F Hillger et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Facilitated transport of a Dpp/Scw heterodimer by Sog/Tsg leads to robust patterning of the Drosophila blastoderm embryo
O Shimmi et al.
CELL (2005)
Type I transforming growth factor β receptor binds to and activates phosphatidylinositol 3-kinase
JY Yi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Adenoviral gene transfer allows Smad-responsive gene promoter analyses and delineation of type I receptor usage of transforming growth factor-beta family ligands in cultured human granulosa luteal cells
N Kaivo-Oja et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2005)
TGF-β signaling and the fibrotic response
A Leask et al.
FASEB JOURNAL (2004)
Molecular recognition of BMP-2 and BMP receptor IA
S Keller et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2004)
A flexible activin explains the membrane-dependent cooperative assembly of TGF-β family receptors
J Greenwald et al.
MOLECULAR CELL (2004)
Molecular recognition in bone morphogenetic protein (BMP)/receptor interaction
W Sebald et al.
BIOLOGICAL CHEMISTRY (2004)
An activin mutant with disrupted ALK4 binding blocks signaling via type II receptors
CA Harrison et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Nodal inhibits differentiation of human embryonic stem cells along the neuroectodermal default pathway
L Vallier et al.
DEVELOPMENTAL BIOLOGY (2004)
Brief report -: Myostatin mutation associated with gross muscle hypertrophy in a child
M Schuelke et al.
NEW ENGLAND JOURNAL OF MEDICINE (2004)
Integrin αvβ6-mediated activation of latent TGF-β requires the latent TGF-β binding protein-1
JP Annes et al.
JOURNAL OF CELL BIOLOGY (2004)
Activin isoforms signal through type I receptor serine/threonine kinase ALK7
K Tsuchida et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2004)
Myostatin signals through a transforming growth factor β-like signaling pathway to block adipogenesis
A Rebbapragada et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
Osteogenic activity of the fourteen types of human bone morphogenetic proteins (BMPs)
HW Cheng et al.
JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME (2003)
A role for BMP heterodimers in roof plate-mediated repulsion of commissural axons
SJ Butler et al.
NEURON (2003)
Structures of an ActRIIB:activin A complex reveal a novel binding mode for TGF-β ligand:receptor interactions
TB Thompson et al.
EMBO JOURNAL (2003)
The BMP7/ActRII extracellular domain complex provides new insights into the cooperative nature of receptor assembly
J Greenwald et al.
MOLECULAR CELL (2003)
Multiple joint and skeletal patterning defects caused by single and double mutations in the mouse Gdf6 and Gdf5 genes
SH Settle et al.
DEVELOPMENTAL BIOLOGY (2003)
Molecular basis of bone morphogenetic protein-15 signaling in granulosa cells
RK Moore et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
EGF-CFC proteins are essential coreceptors for the TGF-beta signals Vg1 and GDF1
SK Cheng et al.
GENES & DEVELOPMENT (2003)
Structural basis of BMP signalling inhibition by the cystine knot protein Noggin
J Groppe et al.
NATURE (2002)
A novel function of bone morphogenetic protein-15 in the pituitary: Selective synthesis and secretion of FSH by gonadotropes
F Otsuka et al.
ENDOCRINOLOGY (2002)
Genetic analysis of the mammalian transforming growth factor-β superfamily
H Chang et al.
ENDOCRINE REVIEWS (2002)
Dynamics-modulated biological activity of transforming growth factor β3
EV Bocharov et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Nodal activity in the node governs left-right asymmetry
J Brennan et al.
GENES & DEVELOPMENT (2002)
Bone morphogenetic protein receptor type II is a receptor for growth differentiation factor-9
UA Vitt et al.
BIOLOGY OF REPRODUCTION (2002)
The orphan receptor ALK7 and the Activin receptor ALK4 mediate signaling by Nodal proteins during vertebrate development
E Reissmann et al.
GENES & DEVELOPMENT (2001)
Bmp6 and Bmp7 are required for cushion formation and septation in the developing mouse heart
RY Kim et al.
DEVELOPMENTAL BIOLOGY (2001)
Anti-Mullerian hormone and its receptors
N Josso et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2001)
The BMP family member Gdf7 is required for seminal vesicle growth, branching morphogenesis, and cytodifferentiation
S Settle et al.
DEVELOPMENTAL BIOLOGY (2001)
The L3 loop and C-terminal phosphorylation jointly define Smad protein trimerization
BM Chacko et al.
NATURE STRUCTURAL BIOLOGY (2001)
Chance and necessity: the evolution of morphological complexity and diversity
SB Carroll
NATURE (2001)
Gdf11 is a negative regulator of chondrogenesis and myogenesis in the developing chick limb
LW Gamer et al.
DEVELOPMENTAL BIOLOGY (2001)
Bone morphogenetic protein-3 is a negative regulator of bone density
A Daluiski et al.
NATURE GENETICS (2001)
GDNF -: a stranger in the TGF-β superfamily?
M Saarma
EUROPEAN JOURNAL OF BIOCHEMISTRY (2000)
How cells read TGF-β signals
J Massagué
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2000)
BMP-2 antagonists emerge from alterations in the low-affinity binding epitope for receptor BMPR-II
T Kirsch et al.
EMBO JOURNAL (2000)
Differential expressions of BMP family genes during chondrogenic differentiation of mouse ATDC5 cells
H Akiyama et al.
CELL STRUCTURE AND FUNCTION (2000)
Transcriptional control by the TGF-β/Smad signaling system
J Massagué et al.
EMBO JOURNAL (2000)
Activin receptor-like kinase 1 modulates transforming growth factor-β1 signaling in the regulation of angiogenesis
SP Oh et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
TGF beta-related pathways - role of Caenorhabditis elegans development
GI Patterson et al.
TRENDS IN GENETICS (2000)
Share Paper
