Journal
FEBS LETTERS
Volume 586, Issue 18, Pages 2882-2890Publisher
WILEY
DOI: 10.1016/j.febslet.2012.07.044
Keywords
Protocell; Vesicle; Bilayer membrane
Funding
- NSF
- U.S. Department of Energy, Office of Basic Energy Sciences, Division of Materials Sciences and Engineering [DE-FG02-11ER46810]
- Direct For Mathematical & Physical Scien
- Division Of Materials Research [1120901] Funding Source: National Science Foundation
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We are on the verge of producing synthetic cells, or protocells, in which some, many or all of the tasks of a real biological cell are harnessed into a synthetic platform. Such advances are made possible through genetic engineering, microfabrication technologies, and the development of cellular membranes from new surfactants that extend beyond phospholipids in stability and chemical control, and can be used to introduce designer functionality into membranes and cells. We review some of the recent advances in the development of synthetic cells and suggest future exciting directions. (C) 2012 Federation of European Biochemical Societies. Published by Elsevier B. V. All rights reserved.
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