Journal
FEBS LETTERS
Volume 586, Issue 22, Pages 3980-3985Publisher
WILEY
DOI: 10.1016/j.febslet.2012.09.029
Keywords
Galactose catabolism; Regulation; Oxido-reductive pathway; Leloir pathway; Aspergillus niger
Funding
- Dutch Technology Foundation STW
- Applied Science division of NWO
- Technology Program of the Ministry of Economic Affairs [UGC 07938]
- Netherlands Organisation for Scientific Research (NWO)
- Netherlands Genomics Initiative [93511035]
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Galactose catabolism in Aspergillus nidulans is regulated by at least two regulators, GalR and GalX. In Aspergillus niger only GalX is present, and its role in D-galactose catabolism in this fungus was investigated. Phenotypic and gene expression analysis of a wild type and a galX disruptant revealed that GalX regulates the D-galactose oxido-reductive pathway, but not the Leloir pathway in A. niger. (c) 2012 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.
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