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JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
ATR-dependent phosphorylation of DNA-dependent protein kinase catalytic subunit in response to UV-induced replication stress
Hirohiko Yajima et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
The activation loop phosphorylation of protein kinase D is an early marker of neuronal DNA damage
Cagri G. Besirli et al.
JOURNAL OF NEUROCHEMISTRY (2006)
Phosphorylation of Chk1 by ATR is antagonized by a Chk1-regulated protein phosphatase 2A circuit
Van Leung-Pineda et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
Differential roles of ATM- and Chk2-mediated phosphorylations of Hdmx in response to DNA damage
Yaron Pereg et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
Wip1 phosphatase modulates ATM-dependent signaling pathways
Sathyavageeswaran Shreeram et al.
MOLECULAR CELL (2006)
ATM engages autodegradation of the E3 ubiquitin ligase COP1 after DNA damage
David Dornan et al.
SCIENCE (2006)
Inhibition of the CaM-kinases augments cell death in response to oxygen radicals and oxygen radical inducing cancer therapies in MCF-7 human breast cancer cells
Oswaldo G. Rodriguez-Mora et al.
CANCER BIOLOGY & THERAPY (2006)
The ATM-mediated DNA-damage response: taking shape
Yosef Shiloh
TRENDS IN BIOCHEMICAL SCIENCES (2006)
JNK pathway mediates apoptotic cell death induced by tumor suppressor LKB1 in Drosophila
J. H. Lee et al.
CELL DEATH AND DIFFERENTIATION (2006)
BubR1 is involved in regulation of DNA damage responses
Y. Fang et al.
ONCOGENE (2006)
Priming phosphorylation of Chk2 by polo-like kinase 3 (Plk3) mediates its full activation by ATM and a downstream checkpoint in response to DNA damage
EM Bahassi et al.
MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS (2006)
Rapid activation of ATR by ionizing radiation requires ATM and Mre11
JS Myers et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells
K Ito et al.
NATURE MEDICINE (2006)
Src tyrosine kinase inhibitor PP2 suppresses ERK1/2 activation and epidermal growth factor receptor transactivation by X-irradiation
ZP Li et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
Protein phosphatase 2A antagonizes ATM and ATR in a Cdk2- and Cdc7-independent DNA damage checkpoint
P Petersen et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
Molecular linkage between the kinase ATM and NF-κB signaling in response to genotoxic stimuli (Publication with Expression of Concern. See vol. 371, pg. 1002, 2021)
ZH Wu et al.
SCIENCE (2006)
mTOR inhibition induces upstream receptor tyrosine kinase signaling and activates Akt
KE O'Reilly et al.
CANCER RESEARCH (2006)
Rapid PIKK-dependent release of Chk1 from chromatin promotes the DNA-damage checkpoint response
VAJ Smits et al.
CURRENT BIOLOGY (2006)
Inhibition of Aurora A in response to DNA damage
A Krystyniak et al.
ONCOGENE (2006)
ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks
A Jazayeri et al.
NATURE CELL BIOLOGY (2006)
γ-H2AX dephosphorylation by protein phosphatase 2A facilitates DNA double-strand break repair
D Chowdhury et al.
MOLECULAR CELL (2005)
DNA damage regulates Chk2 association with chromatin
J Li et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Inhibition of Aurora-B kinase activity by poly(ADP-ribosyl)ation in response to DNA damage
L Monaco et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
The radioresistance kinase TLK1B protects the cells by promoting repair of double strand breaks
G Sunavala-Dossabhoy et al.
BMC MOLECULAR BIOLOGY (2005)
Radiation-induced epidermal growth factor receptor nuclear import is linked to activation of DNA-dependent protein kinase
K Dittmann et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
ATM-mediated phosphorylations inhibit Mdmx/Mdm2 stabilization by HAUSP in favor of p53 activation
E Meulmeester et al.
CELL CYCLE (2005)
The coordinate regulation of the p53 and rnTOR pathways in cells
ZH Feng et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
CK2 inhibits apoptosis and changes its cellular localization following ionizing radiation
K Yamane et al.
CANCER RESEARCH (2005)
Phosphorylation of Hdmx mediates its Hdm2- and ATM-dependent degradation in response to DNA damage
Y Pereg et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Co-activation of ERK, NF-κB, and GADD45β in response to ionizing radiation
T Wang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Regulation of CHK2 by DNA-dependent protein kinase
J Li et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
TTK/hMps1 participates in the regulation of DNA damage checkpoint response by phosphorylating CHK2 on threonine 68
JH Wei et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
JNK phosphorylation of 14-3-3 proteins regulates nuclear targeting of c-Abl in the apoptotic response to DNA damage
K Yoshida et al.
NATURE CELL BIOLOGY (2005)
Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex
DD Sarbassov et al.
SCIENCE (2005)
Full activation of PKB/Akt in response to insulin or ionizing radiation is mediated through ATM
JG Viniegra et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
MAPKAP kinase-2 is a cell cycle checkpoint kinase that regulates the G2/M transition and S phase progression in response to UV irradiation
IA Manke et al.
MOLECULAR CELL (2005)
Phosphorylation of Plk1 at S137 and T210 is inhibited in response to DNA damage
L Tsvetkov et al.
CELL CYCLE (2005)
Cdc25C phosphorylation on serine 191 by Plk3 promotes its nuclear translocation
ELM Bahassi et al.
ONCOGENE (2004)
Translation of the radioresistance kinase TLK1B is induced by γ-irradiation through activation of mTOR and phosphorylation of 4E-BP1 -: art. no. 1
G Sunavala-Dossabhoy et al.
BMC MOLECULAR BIOLOGY (2004)
The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress
RJ Shaw et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
ATM and the catalytic subunit of DNA-dependent protein kinase activate NF-κB through a common MEK extracellular signal-regulated kinase/p90rsk signaling pathway in response to distinct forms of DNA damage
GR Panta et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Recovery from DNA damage checkpoint arrest by PP1-mediated inhibition of Chk1
NR den Elzen et al.
EMBO JOURNAL (2004)
Requirement of protein phosphatase 5 in DNA-damage-induced ATM activation
A Ali et al.
GENES & DEVELOPMENT (2004)
Identification of a PKB/Akt hydrophobic motif Ser-473 kinase as DNA-dependent protein kinase
JH Feng et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Inhibition of centrosome separation after DNA damage: A role for Nek2
L Fletcher et al.
RADIATION RESEARCH (2004)
The TSC1-2 tumor suppressor controls insulin-PI3K signaling via regulation of IRS proteins
LS Harrington et al.
JOURNAL OF CELL BIOLOGY (2004)
Rapamycin inhibits doxorubicin-induced NF-κB/Rel nuclear activity and enhances the apoptosis of melanoma cells
MF Romano et al.
EUROPEAN JOURNAL OF CANCER (2004)
The LKB1 tumor suppressor negatively regulates mTOR signaling
RJ Shaw et al.
CANCER CELL (2004)
Claspin and the activated form of ATR-ATRIP collaborate in the activation of Chk1
A Kumagai et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
The stress kinase MRK contributes to regulation of DNA damage checkpoints through a p38γ-independent pathway
E Tosti et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Autophosphorylation of ataxia-telangiectasia mutated is regulated by protein phosphatase 2A
AA Goodarzi et al.
EMBO JOURNAL (2004)
Activation of Aurora-A kinase by protein phosphatase inhibitor-2, a bifunctional signaling protein
DL Satinover et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells
K Ito et al.
NATURE (2004)
Activation loop phosphorylation controls protein kinase D-dependent activation of nuclear factor κB
P Storz et al.
MOLECULAR PHARMACOLOGY (2004)
Advances in protein kinase B signalling:: AKTion on multiple fronts
DP Brazil et al.
TRENDS IN BIOCHEMICAL SCIENCES (2004)
An oncogenic tyrosine kinase inhibits DNA repair and DNAdamage-induced Bcl-X-L deamidation in T cell transformation
R Zhao et al.
CANCER CELL (2004)
Differential contribution of inhibitory phosphorylation of CDC2 and CDK2 for unperturbed cell cycle control and DNA integrity checkpoints
JPH Chow et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Regulation of Cdc2/cyclin B activation in Xenopus egg extracts via inhibitory phosphorylation of Cdc25C phosphatase by Ca2+/calmodium-dependent kinase II
JRA Hutchins et al.
MOLECULAR BIOLOGY OF THE CELL (2003)
DNA damage during the spindle-assembly checkpoint degrades CDC25A, inhibits cyclin-CDC2 complexes, and reverses cells to interphase
JPH Chow et al.
MOLECULAR BIOLOGY OF THE CELL (2003)
Suppression of Tousled-like kinase activity after DNA damage or replication block requires ATM, NBS1 and Chk1
DR Krause et al.
ONCOGENE (2003)
Human CLK2 links cell cycle progression, apoptosis, and telomere length regulation
N Jiang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Ataxia-telangiectasia-mutated (ATM) and NBS1-dependent phosphorylation of Chk1 on Ser-317 in response to ionizing radiation
M Gatei et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
The p38 and MK2 kinase cascade phosphorylates tuberin, the tuberous sclerosis 2 gene product, and enhances its interaction with 14-3-3
Y Li et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
The death domain kinase RIP has an essential role in DNA damage-induced NF-κB activation
GM Hur et al.
GENES & DEVELOPMENT (2003)
Human Tousled like kinases are targeted by an ATM- and Chk1-dependent DNA damage checkpoint
A Groth et al.
EMBO JOURNAL (2003)
ATM and related protein kinases: Safeguarding genome integrity
Y Shiloh
NATURE REVIEWS CANCER (2003)
One-thousand-and-one substrates of protein kinase CK2?
F Meggio et al.
FASEB JOURNAL (2003)
Identification of a novel protein kinase mediating Akt survival signaling to the ATM protein
A Suzuki et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Role of the insulin-like growth factor I insulin receptor substrate 1 axis in Rad51 trafficking and DNA repair by homologous recombination
J Trojanek et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
Protein kinases and their involvement in the cellular responses to genotoxic stress
J Yang et al.
MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH (2003)
Activation of SAPK/JNK signaling by protein kinase Cδ in response to DNA damage
K Yoshida et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Ionizing radiation induces ataxia telangiectasia mutated kinase (ATM)-mediated phosphorylation of LKB1/STK11 at Thr-366
GP Sapkota et al.
BIOCHEMICAL JOURNAL (2002)
Ionizing radiation activates nuclear protein phosphatase-1 by ATM-dependent dephosphorylation
CY Guo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Nek11, a new member of the NIMA family of kinases, involved in DNA replication and genotoxic stress responses
K Noguchi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Mammalian Polo-like kinase 3 (PIU) is a multifunctional protein involved in stress response pathways
EM Bahassi et al.
ONCOGENE (2002)
Ionizing radiation activates Erb-B receptor dependent Akt and p70 S6 kinase signaling in carcinoma cells
JN Contessa et al.
ONCOGENE (2002)
A role for PI 3-kinase and PKB activity in the G2/M phase of the cell cycle
E Shtivelman et al.
CURRENT BIOLOGY (2002)
Constitutive association of BRCA1 and c-Abl and its ATM-dependent disruption after irradiation
N Foray et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
MRK, a mixed lineage kinase-related molecule that plays a role in γ-radiation-induced cell cycle arrest
EA Gross et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
ERK activation mediates cell cycle arrest and apoptosis after DNA damage independently of p53
DM Tang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Plk1 promotes nuclear translocation of human Cdc25C during prophase
F Toyoshima-Morimoto et al.
EMBO REPORTS (2002)
Inhibition of polo-like kinase-1 by DNA damage occurs in an ATM- or ATR-dependent fashion
MATM van Vugt et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Involvement of DNA-dependent protein kinase in regulation of stress-induced JNK activation
SJ Park et al.
DNA AND CELL BIOLOGY (2001)
S phase dependence and involvement of NF-kappaB activating kinase to NF-kappaB activation by camptothecin
Y Habraken et al.
BIOCHEMICAL PHARMACOLOGY (2001)
TAK1 is a ubiquitin-dependent kinase of MKK and IKK
C Wang et al.
NATURE (2001)
Downregulation of the type 1 insulin-like growth factor receptor in mouse melanoma cells is associated with enhanced radiosensitivity and impaired activation of Atm kinase
VM Macaulay et al.
ONCOGENE (2001)
Interaction of hematopoietic progenitor kinase 1 and c-abl tyrosine kinase in response to genotoxic stress
Y Ito et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Initiation of a G2/M checkpoint after ultraviolet radiation requires p38 kinase
DV Bulavin et al.
NATURE (2001)
ATM is required for IκB kinase (IKK) activation in response to DNA double strand breaks
NX Li et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Regulation of DNA-dependent protein kinase activity by ionizing radiation-activated Abl kinase is an ATM-dependent process
S Shangary et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Role for Lyn tyrosine kinase as a regulator of stress-activated protein kinase activity in response to DNA damage
K Yoshida et al.
MOLECULAR AND CELLULAR BIOLOGY (2000)
Transactivation of the EGF receptor mediates IGF-1-stimulated Shc phosphorylation and ERK1/2 activation in COS-7 cells
FL Roudabush et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Involvement of the MKK6-p38γ cascade in γ-radiation-induced cell cycle arrest
XF Wang et al.
MOLECULAR AND CELLULAR BIOLOGY (2000)
Activation of MEK kinase 1 by the c-Abl protein tyrosine kinase in response to DNA damage
S Kharbanda et al.
MOLECULAR AND CELLULAR BIOLOGY (2000)
DNA-damaging agents cause inactivation of translational regulators linked to mTOR signalling
AR Tee et al.
ONCOGENE (2000)
Cables links Cdk5 and c-Abl and facilitates Cdk5 tyrosine phosphorylation, kinase upregulation, and neurite outgrowth
LR Zukerberg et al.
NEURON (2000)
Regulation of the rapamycin and FKBP-target 1/mammalian target of rapamycin and cap-dependent initiation of translation by the c-Abl protein-tyrosine kinase
V Kumar et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Polo-like kinase-1 is a target of the DNA damage checkpoint
VAJ Smits et al.
NATURE CELL BIOLOGY (2000)