Journal
FEBS LETTERS
Volume 584, Issue 10, Pages 2102-2111Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.febslet.2010.01.037
Keywords
Chloride channel; ClC; CLIC; Bestrophin; Golgi pH regulator
Funding
- NHLBI NIH HHS [R01 HL092131, R01 HL092131-01A2] Funding Source: Medline
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Proteins implicated as intracellular chloride channels include the intracellular ClC proteins, the bestrophins, the cystic fibrosis transmembrane conductance regulator, the CLICs, and the recently described Golgi pH regulator. This paper examines current hypotheses regarding roles of intracellular chloride channels and reviews the evidence supporting a role in intracellular chloride transport for each of these proteins. (C) 2010 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.
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