4.5 Review

Post-translational modifications in host cells during bacterial infection

Journal

FEBS LETTERS
Volume 584, Issue 13, Pages 2748-2758

Publisher

ELSEVIER SCIENCE BV
DOI: 10.1016/j.febslet.2010.05.012

Keywords

Rho GTPase; Cytoskeleton; Ubiquitin; MAPK; SUMO; Pathogenesis; Listeria

Funding

  1. Institut Pasteur
  2. Inserm
  3. INRA
  4. ERC [233348]
  5. Foundation le Roch Les Mousquetaires
  6. Association pour la Recherche sur le Cancer
  7. European Research Council (ERC) [233348] Funding Source: European Research Council (ERC)

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Post-translational modification of proteins is a widespread mechanism used by both prokaryotic and eukaryotic cells to modify the activity of key factors that plays fundamental roles in cellular physiology. This review focuses on how bacterial pathogens can interfere with host post-translational modifications to promote their own survival and replication. (C) 2010 Federation of European Biochemical Societies. Published by Elsevier B. V. All rights reserved.

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