Journal
FEBS LETTERS
Volume 585, Issue 1, Pages 143-147Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.febslet.2010.11.025
Keywords
14-3-3 Proteins; Nutrient; Metabolism; Plant
Funding
- RIKEN President's Discretionary Fund
- Monsanto Company
- USDA [NRI-2005-02518]
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14-3-3 Proteins regulate many cellular processes by binding to phosphorylated proteins. Previous findings suggest a connection between three 14-3-3 isoforms and plant nutrient signaling. To better understand how these 14-3-3s regulate metabolism in response to changes in plant nutrient status, putative new targets involved in nitrogen (N) and sulfur (S) metabolisms have been identified. The interactions between these 14-3-3s and multiple proteins involved in N and S metabolism and altered activity of the target proteins were confirmed in planta. Using a combination of methods, this work elucidates how 14-3-3s function as modulators of plant N and S metabolic pathways. (C) 2010 Federation of European Biochemical Societies. Published by Elsevier B. V. All rights reserved.
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