4.5 Review

IQGAPs in cancer: A family of scaffold proteins underlying tumorigenesis

Related references

Note: Only part of the references are listed.
Review Cell Biology

Protein scaffolds in MAP kinase signalling

Matthew D. Brown et al.

CELLULAR SIGNALLING (2009)

Review Oncology

Multitargeted cancer prevention by quercetin

Akira Murakami et al.

CANCER LETTERS (2008)

Article Cell Biology

Assembly and biological role of podosomes and invadopodia

Mario Gimona et al.

CURRENT OPINION IN CELL BIOLOGY (2008)

Article Cell Biology

Wnt/β-catenin signaling:: new (and old) players and new insights

He Huang et al.

CURRENT OPINION IN CELL BIOLOGY (2008)

Article Biochemistry & Molecular Biology

Actin Pedestal Formation by Enteropathogenic Escherichia coli Is Regulated by IQGAP1, Calcium, and Calmodulin

Matthew D. Brown et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2008)

Article Cell Biology

A dual role for IQGAP1 in regulating exocytosis

Eric N. Rittmeyer et al.

JOURNAL OF CELL SCIENCE (2008)

Article Oncology

Silencing of IQGAP1 by shRNA inhibits the invasion of ovarian carcinoma HO-8910PM cells in vitro

Pei-Xin Dong et al.

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2008)

Article Biochemistry & Molecular Biology

Development of hepatocellular carcinoma in Iqgap2-deficient mice is IQGAP1 dependent

Valentina A. Schmidt et al.

MOLECULAR AND CELLULAR BIOLOGY (2008)

Article Cell Biology

IQGAP3 regulates cell proliferation through the Ras/ERK signalling cascade

Hisashi Nojima et al.

NATURE CELL BIOLOGY (2008)

Review Biochemistry & Molecular Biology

Cadherins and cancer: how does cadherin dysfunction promote tumor progression?

A. Jeanes et al.

ONCOGENE (2008)

Article Multidisciplinary Sciences

IQGAP1-Dependent Signaling Pathway Regulates Endothelial Cell Proliferation and Angiogenesis

Rosana D. Meyer et al.

PLOS ONE (2008)

Article Multidisciplinary Sciences

被撤回的出版物: A genomic approach to colon cancer risk stratification yields biologic insights into therapeutic opportunities (Retracted Article. See vol 106, pg 6878, 2009)

Katherine S. Garman et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Article Biochemistry & Molecular Biology

IQGAP1 stimulates proliferation and enhances tumorigenesis of human breast epithelial cells

Lorraine Jadeski et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2008)

Article Biochemistry & Molecular Biology

Get to grips: steering local actin dynamics with IQGAPs

Dominique T. Brandt et al.

EMBO REPORTS (2007)

Article Biochemistry & Molecular Biology

IQGAP1 regulates Salmonella invasion through interactions with actin, Rac1, and Cdc42

Matthew D. Brown et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Article Developmental Biology

IQGAP2 is required for the cadherin-mediated cell-to-cell adhesion in Xenopus laevis embryos

Sawako Yamashiro et al.

DEVELOPMENTAL BIOLOGY (2007)

Article Cell Biology

Dia1 and IQGAP1 interact in cell migration and phagocytic cup formation

Dominique T. Brandt et al.

JOURNAL OF CELL BIOLOGY (2007)

Article Multidisciplinary Sciences

IQGAP1 modulates activation of B-Raf

Jian-Guo Ren et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Review Biochemistry & Molecular Biology

Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer

P. J. Roberts et al.

ONCOGENE (2007)

Article Clinical Neurology

IQGAP1 and IGFBP2: Valuable biomarkers for determining prognosis in glioma patients

Kerrie L. McDonald et al.

JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2007)

Article Cell Biology

IQGAP3, a novel effector of Rac1 and Cdc42, regulates neurite outgrowth

Shujie Wang et al.

JOURNAL OF CELL SCIENCE (2007)

Article Cell Biology

IQGAP1 regulates cell motility by linking growth factor signaling to actin assembly

Lorena B. Bensenor et al.

JOURNAL OF CELL SCIENCE (2007)

Article Cell Biology

Multiple proteins mediate IQGAP1-stimulated cell migration

Jennifer M. Mataraza et al.

CELLULAR SIGNALLING (2007)

Article Biochemistry & Molecular Biology

The role of scaffold proteins in MEK/ERK signalling

D. B. Sacks

BIOCHEMICAL SOCIETY TRANSACTIONS (2006)

Article Oncology

IQGAP1 protein specifies amplifying cancer cells in glioblastoma multiforme

Laurent Balenci et al.

CANCER RESEARCH (2006)

Review Biochemistry & Molecular Biology

Tumor metastasis: mechanistic insights and clinical challenges

Patricia S. Steeg

NATURE MEDICINE (2006)

Article Biochemistry & Molecular Biology

The exocyst defrocked, a framework of rods revealed

Mary Munson et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2006)

Article Oncology

Clinical significance of TROP2 expression in colorectal cancer

Takahiro Ohmachi et al.

CLINICAL CANCER RESEARCH (2006)

Review Cell Biology

IQGAP1 in cellular signaling: bridging the GAP

Matthew D. Brown et al.

TRENDS IN CELL BIOLOGY (2006)

Review Oncology

Invadopodia: specialized cell structures for cancer invasion

Alissa M. Weaver

CLINICAL & EXPERIMENTAL METASTASIS (2006)

Article Neurosciences

Calcium-dependent interaction of Lis1 with IQGAP1 and Cdc42 promotes neuronal motility

SS Kholmanskikh et al.

NATURE NEUROSCIENCE (2006)

Review Cell Biology

Coordinating ERK/MAPK signalling through scaffolds and inhibitors

W Kolch

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2005)

Article Biochemistry & Molecular Biology

IQGAP1 is a scaffold for mitogen-activated protein kinase signaling

M Roy et al.

MOLECULAR AND CELLULAR BIOLOGY (2005)

Article Cell Biology

IQGAP1: A key regulator of adhesion and migration

J Noritake et al.

JOURNAL OF CELL SCIENCE (2005)

Article Oncology

Nucleotide variants within the IQGAPI gene in diffuse-type gastric cancers

LE Morris et al.

GENES CHROMOSOMES & CANCER (2005)

Article Gastroenterology & Hepatology

IQGAPs are differentially expressed and regulated in polarized gastric epithelial cells

CS Chew et al.

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2005)

Article Biochemistry & Molecular Biology

IQGAP1 binds ERK2 and modulates its activity

M Roy et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2004)

Review Multidisciplinary Sciences

Convergence of Wnt, β-catenin, and cadherin pathways

WJ Nelson et al.

SCIENCE (2004)

Review Oncology

A census of human cancer genes

PA Futreal et al.

NATURE REVIEWS CANCER (2004)

Review Biochemistry & Molecular Biology

Principles of tumor suppression

CJ Sherr

Review Cell Biology

The RAF proteins take centre stage

C Wellbrock et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2004)

Article Biochemistry & Molecular Biology

MEK1 and MEK2, different regulators of the G1/S transition

S Ussar et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2004)

Article Biochemistry & Molecular Biology

IQGAP1 promotes cell motility and invasion

JM Mataraza et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)

Review Biochemistry & Molecular Biology

IQGAP proteins are integral components of cytoskeletal regulation

MW Briggs et al.

EMBO REPORTS (2003)

Review Biochemistry & Molecular Biology

IQGAP1 as signal integrator:: Ca2+, calmodulin, Cdc42 and the cytoskeleton

MW Briggs et al.

FEBS LETTERS (2003)

Article Cell Biology

Localization of two IQGAPs in cultured cells and early embryos of Xenopus laevis

S Yamashiro et al.

CELL MOTILITY AND THE CYTOSKELETON (2003)

Review Multidisciplinary Sciences

Rho GTPases in cell biology

S Etienne-Manneville et al.

NATURE (2002)

Article Biochemistry & Molecular Biology

IQGAP1 is a component of Cdc42 signaling to the cytoskeleton

JM Swart-Mataraza et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2002)

Article Multidisciplinary Sciences

Mutations of the BRAF gene in human cancer

H Davies et al.

NATURE (2002)

Review Oncology

RHO-GTPases and cancer

E Sahai et al.

NATURE REVIEWS CANCER (2002)

Article Biochemistry & Molecular Biology

IQGAP1-mediated stimulation of transcriptional co-activation by beta-catenin is modulated by calmodulin

MW Briggs et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2002)

Article Multidisciplinary Sciences

Genomic analysis of metastasis reveals an essential role for RhoC

EA Clark et al.

NATURE (2000)