Journal
FEBS LETTERS
Volume 582, Issue 14, Pages 2004-2016Publisher
WILEY
DOI: 10.1016/j.febslet.2008.02.067
Keywords
nuclear pore complex; nuclear assembly; cell cycle; nucleoporin
Ask authors/readers for more resources
In eukaryotes, all macromolecules traffic between the nucleus and the cytoplasm through nuclear pore complexes (NPCs), which are among the largest supramolecular assemblies in cells. Although their composition in yeast and metazoa is well characterized, understanding how NPCs are assembled and form the pore through the double membrane of the nuclear envelope and how both processes are controlled still remains a challenge. Here, we summarize what is known about the biogenesis of NPCs throughout the cell cycle with special focus on the membrane reorganization and the regulation that go along with NPC assembly. (C) 2008 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available