Journal
FEBS LETTERS
Volume 582, Issue 23-24, Pages 3257-3262Publisher
WILEY
DOI: 10.1016/j.febslet.2008.09.026
Keywords
p14/p19ARF; Proteasome; Cell stress sensor; REG-gamma; TBP-1/PSMC3
Funding
- A.I.R.C.
Ask authors/readers for more resources
The tumor suppressor ARF is one of the most important oncogenic stress sensors in mammalian cells. Its effect is exerted through the interaction with different cellular partners, often resulting in their functional inactivation. This review focuses on the role played by the proteasome in ARF regulation of protein turnover and the function of most of its interacting partners. Specific proteasome components appear to be involved in the regulation of ARF turnover, bringing to light a complex network of interactions between ARF and the proteasome. (C) 2008 Federation of European Biochemical Societies. Published by Elsevier B. V. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available