Related references
Note: Only part of the references are listed.A miniaturized assay for measuring small molecule phosphorylation in the presence of complex matrices
Christina Spry et al.
ANALYTICAL BIOCHEMISTRY (2014)
Structural characterization of a new N-substituted pantothenamide bound to pantothenate kinases from Klebsiella pneumoniae and Staphylococcus aureus
Scott J. Hughes et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2014)
Combination of Pantothenamides with Vanin Inhibitors as a Novel Antibiotic Strategy against Gram-Positive Bacteria
Patrick A. M. Jansen et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2013)
Low-Molecular-Weight Thiols in Thiol-Disulfide Exchange
Koen Van Laer et al.
ANTIOXIDANTS & REDOX SIGNALING (2013)
Pantothenamides Are Potent, On-Target Inhibitors of Plasmodium falciparum Growth When Serum Pantetheinase Is Inactivated
Christina Spry et al.
PLOS ONE (2013)
Crystal structures of Klebsiella pneumoniae pantothenate kinase in complex with N-substituted pantothenamides
Buren Li et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2013)
Structural Modification of Pantothenamides Counteracts Degradation by Pantetheinase and Improves Antiplasmodial Activity
Marianne de Villiers et al.
ACS MEDICINAL CHEMISTRY LETTERS (2013)
The Antibiotic CJ-15,801 Is an Antimetabolite that Hijacks and Then Inhibits CoA Biosynthesis
Renier van der Westhuyzen et al.
CHEMISTRY & BIOLOGY (2012)
Geminal dialkyl derivatives of N-substituted pantothenamides: Synthesis and antibacterial activity
T. Olukayode Akinnusi et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2011)
Impaired Coenzyme A metabolism affects histone and tubulin acetylation in Drosophila and human cell models of pantothenate kinase associated neurodegeneration
Katarzyna Siudeja et al.
EMBO MOLECULAR MEDICINE (2011)
Pantethine Rescues Phosphopantothenoylcysteine Synthetase and Phosphopantothenoylcysteine Decarboxylase Deficiency in Escherichia coli but Not in Pseudomonas aeruginosa
Carl J. Balibar et al.
JOURNAL OF BACTERIOLOGY (2011)
Antibacterial Activity of N-Pentylpantothenamide Is Due to Inhibition of Coenzyme A Synthesis
Jacob Thomas et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2010)
Biocatalytic Production of Coenzyme A Analogues
Erick Strauss et al.
CHEMCATCHEM (2010)
Structural basis for substrate binding and the catalytic mechanism of type III pantothenate kinase
Kun Yang et al.
BIOCHEMISTRY (2008)
Antibiotic evaluation and in vivo analysis of alkynyl Coenzyme A antimetabolites in Escherichia coli
Andrew C. Mercer et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2008)
Development of a method for the parallel synthesis and purification of N-substituted pantothenamides, known inhibitors of coenzyme A biosynthesis and utilization
Marianne van Wyk et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2008)
Coenzyme A biosynthesis: an antimicrobial drug target
Christina Spry et al.
FEMS MICROBIOLOGY REVIEWS (2008)
Structure of the type III pantothenate kinase from Bacillus anthracis at 2.0 Å resolution:: Implications for coenzyme A-dependent redox biology
Nathan I. Nicely et al.
BIOCHEMISTRY (2007)
Chemical knockout of pantothenate kinase reveals the metabolic and genetic program responsible for hepatic coenzyme a homeostasis
Yong-Mei Zhang et al.
CHEMISTRY & BIOLOGY (2007)
One-pot preparation of coenzyme A analogues via an improved chemoenzymatic synthesis of pre-CoA thioester synthons
Marianne van Wyk et al.
CHEMICAL COMMUNICATIONS (2007)
The ubiquitous carrier protein - a window to metabolite biosynthesis
Andrew C. Mercer et al.
NATURAL PRODUCT REPORTS (2007)
Synthesis and evaluation of bioorthogonal pantetheine analogues for in vivo protein modification
Jordan L. Meier et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2006)
Crystal structure of a type III pantothenate kinase: Insight into the mechanism of an essential coenzyme A biosynthetic enzyme universally distributed in bacteria
Kun Yang et al.
JOURNAL OF BACTERIOLOGY (2006)
Prokaryotic type II and type III pantothenate kinases: The same monomer fold creates dimers with distinct catalytic properties
Bum Soo Hong et al.
STRUCTURE (2006)
Structure-activity relationships and enzyme inhibition of pantothenamide-type pantothenate kinase inhibitors
KG Virga et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2006)
One-pot chemo-enzymatic synthesis of reporter-modified proteins
AS Worthington et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2006)
The design and synthesis of inhibitors of pantothenate synthetase
Kellie L. Tuck et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2006)
The enigmatic acyl carrier protein phosphodiesterase of Escherichia coli -: Genetic and enzymological characterization
J Thomas et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Characterization of a new pantothenate kinase isoform from Helicobacter pylori.
LA Brand et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
A pantothenate kinase from Staphylococcus aureus refractory to feedback regulation by coenzyme A
R Leonardi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
The structure of the pantothenate kinase•ADP•pantothenate ternary complex reveals the relationship between the binding sites for substrate, allosteric regulator, and antimetabolites
RA Ivey et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Acyl carrier protein is a cellular target for the antibacterial action of the pantothenamide class of pantothenate antimetabolites
YM Zhang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Inhibitors of pantothenate kinase: Novel antibiotics for staphylococcal infections
AE Choudhry et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2003)
The antibiotic activity of N-pentylpantothenamide results from its conversion to ethyldethia-coenzyme A, a coenzyme A antimetabolite
E Strauss et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)