Related references
Note: Only part of the references are listed.In silico Target Fishing for the Potential Targets and Molecular Mechanisms of Baicalein as an Antiparkinsonian Agent: Discovery of the Protective Effects on NMDA Receptor-Mediated Neurotoxicity
Li Gao et al.
CHEMICAL BIOLOGY & DRUG DESIGN (2013)
Computational Drug Repositioning: From Data to Therapeutics
M. R. Hurle et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2013)
Network-based drug repositioning
Zikai Wu et al.
MOLECULAR BIOSYSTEMS (2013)
NCBI GEO: archive for functional genomics data sets-update
Tanya Barrett et al.
NUCLEIC ACIDS RESEARCH (2013)
Molecular Chaperones as Rational Drug Targets for Parkinsons Disease Therapeutics
S. K. Kalia et al.
CNS & Neurological Disorders-Drug Targets (2012)
GPEC: A Cytoscape plug-in for random walk-based gene prioritization and biomedical evidence collection
Duc-Hau Le et al.
COMPUTATIONAL BIOLOGY AND CHEMISTRY (2012)
Applications of Connectivity Map in drug discovery and development
Xiaoyan A. Qu et al.
DRUG DISCOVERY TODAY (2012)
Mitochondrial dysfunction in Parkinson's disease: molecular mechanisms and pathophysiological consequences
Nicole Exner et al.
EMBO JOURNAL (2012)
Protective effects of baicalein against rotenone-induced neurotoxicity in PC12 cells and isolated rat brain mitochondria
Xiao-xiu Li et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2012)
Computational approaches to disease-gene prediction: rationale, classification and successes
Rosario M. Piro et al.
FEBS JOURNAL (2012)
Cellular models to investigate biochemical pathways in Parkinson's disease
Tiziana Alberio et al.
FEBS JOURNAL (2012)
Molecular Chaperones and Co-Chaperones in Parkinson Disease
Hemi Dimant et al.
NEUROSCIENTIST (2012)
Therapeutic target database update 2012: a resource for facilitating target-oriented drug discovery
Feng Zhu et al.
NUCLEIC ACIDS RESEARCH (2012)
Cytoscape 2.8: new features for data integration and network visualization
Michael E. Smoot et al.
BIOINFORMATICS (2011)
mRNA Expression Signatures of Human Skeletal Muscle Atrophy Identify a Natural Compound that Increases Muscle Mass
Steven D. Kunkel et al.
CELL METABOLISM (2011)
A Phase I Study of the Heat Shock Protein 90 Inhibitor Alvespimycin (17-DMAG) Given Intravenously to Patients with Advanced Solid Tumors
Simon Pacey et al.
CLINICAL CANCER RESEARCH (2011)
A New Face and New Challenges for Online Mendelian Inheritance in Man (OMIM®)
Joanna Amberger et al.
HUMAN MUTATION (2011)
The Comparative Toxicogenomics Database: update 2011
Allan Peter Davis et al.
NUCLEIC ACIDS RESEARCH (2011)
Discovery and Preclinical Validation of Drug Indications Using Compendia of Public Gene Expression Data
Marina Sirota et al.
SCIENCE TRANSLATIONAL MEDICINE (2011)
ParkDB: a Parkinson's disease gene expression database
Cristian Taccioli et al.
DATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION (2011)
A general co-expression network-based approach to gene expression analysis: comparison and applications
Jianhua Ruan et al.
BMC SYSTEMS BIOLOGY (2010)
Phase I study of the heat shock protein 90 inhibitor alvespimycin (KOS-1022, 17-DMAG) administered intravenously twice weekly to patients with acute myeloid leukemia
J. E. Lancet et al.
LEUKEMIA (2010)
Efficient Drug Lead Discovery and Optimization
William L. Jorgensen
ACCOUNTS OF CHEMICAL RESEARCH (2009)
Update on Hsp90 Inhibitors in Clinical Trial
Y. S. Kim et al.
CURRENT TOPICS IN MEDICINAL CHEMISTRY (2009)
Heat shock proteins in neurodegenerative diseases: Pathogenic roles and therapeutic implications
Hiroaki Adachi et al.
INTERNATIONAL JOURNAL OF HYPERTHERMIA (2009)
Walking the interactome for prioritization of candidate disease genes
Sebastian Koehler et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2008)
Discovery of agents that eradicate leukemia stem cells using an in silico screen of public gene expression data
Duane C. Hassane et al.
BLOOD (2008)
The chaperone activity of heat shock protein 90 is critical for maintaining the stability of leucine-rich repeat kinase 2
Lizhen Wang et al.
JOURNAL OF NEUROSCIENCE (2008)
L347P PINK1 mutant that fails to bind to Hsp90/Cdc37 chaperones is rapidly degraded in a proteasome-dependent manner
Yasuhiro Moriwaki et al.
NEUROSCIENCE RESEARCH (2008)
PolySearch: a web-based text mining system for extracting relationships between human diseases, genes, mutations, drugs and metabolites
Dean Cheng et al.
NUCLEIC ACIDS RESEARCH (2008)
Proteomic and transcriptomic study on the action of a cytotoxic saponin (Polyphyllin D): Induction of endoplasmic reticulum stress and mitochondria-mediated apoptotic pathways
Fung-Ming Siu et al.
PROTEOMICS (2008)
A genomic pathway approach to a complex disease: Axon guidance and parkinson disease
Timothy G. Lesnick et al.
PLOS GENETICS (2007)
Innovation - The Connectivity Map: a new tool for biomedical research
Justin Lamb
NATURE REVIEWS CANCER (2007)
The connectivity map: Using gene-expression signatures to connect small molecules, genes, and disease
Justin Lamb et al.
SCIENCE (2006)
Convergence of heat shock protein 90 with ubiquitin in filamentous α-synuclein inclusions of α-synucleinopathies
K Uryu et al.
AMERICAN JOURNAL OF PATHOLOGY (2006)
Whole genome expression profiling of the medial and lateral substantia nigra in Parkinson's disease
LB Moran et al.
NEUROGENETICS (2006)
DrugBank: a comprehensive resource for in silico drug discovery and exploration
David S. Wishart et al.
NUCLEIC ACIDS RESEARCH (2006)
Entropy method for determination of weight of evaluating indicators in fuzzy synthetic evaluation for water quality assessment
Zou Zhi-hong et al.
JOURNAL OF ENVIRONMENTAL SCIENCES (2006)
Geldanamycin induces heat shock protein 70 and protects against MPTP-induced dopaminergic neurotoxicity in mice
HY Shen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Altered gene expression profiles reveal similarities and differences between Parkinson disease and model systems
RM Miller et al.
NEUROSCIENTIST (2005)
Cross-platform comparability of microarray technology: Intra-platform consistency and appropriate data analysis procedures are essential
LM Shi et al.
BMC BIOINFORMATICS (2005)
Consensus scoring criteria for improving enrichment in virtual screening
JM Yang et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2005)
Glide: A new approach for rapid, accurate docking and scoring. 2. Enrichment factors in database screening
TA Halgren et al.
JOURNAL OF MEDICINAL CHEMISTRY (2004)
Pharmacological prevention of Parkinson disease in Drosophila
PK Auluck et al.
NATURE MEDICINE (2002)
Significance analysis of microarrays applied to the ionizing radiation response
VG Tusher et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Chronic systemic pesticide exposure reproduces features of Parkinson's disease
R Betarbet et al.
NATURE NEUROSCIENCE (2000)