Related references
Note: Only part of the references are listed.Sumoylation of Vimentin354 Is Associated with PIAS3 Inhibition of Glioma Cell Migration
Oncotarget (2015)
Transcriptional Protein Sp1 Regulates LEDGF Transcription by Directly Interacting with Its Cis-Elements in GC-Rich Region of TATA-Less Gene Promoter
Dhirendra P. Singh et al.
PLOS ONE (2012)
LEDGF gene silencing impairs the tumorigenicity of prostate cancer DU145 cells by abating the expression of Hsp27 and activation of the Akt/ERK signaling pathway
B. Bhargavan et al.
CELL DEATH & DISEASE (2012)
The SUMO protease SENP6 is a direct regulator of PML nuclear bodies
Neil Hattersley et al.
MOLECULAR BIOLOGY OF THE CELL (2011)
Nuclear protein LEDGF/p75 recognizes supercoiled DNA by a novel DNA-binding domain
Kimiko M. Tsutsui et al.
NUCLEIC ACIDS RESEARCH (2011)
GPS2-dependent corepressor/SUMO pathways govern anti-inflammatory actions of LRH-1 and LXRβ in the hepatic acute phase response
Nicolas Venteclef et al.
GENES & DEVELOPMENT (2010)
SUMO functions in constitutive transcription and during activation of inducible genes in yeast
Emanuel Rosonina et al.
GENES & DEVELOPMENT (2010)
SENP1-mediated GATA1 deSUMOylation is critical for definitive erythropoiesis
Luyang Yu et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2010)
SUMOylation of the Lens Epithelium-Derived Growth Factor/p75 Attenuates Its Transcriptional Activity on the Heat Shock Protein 27 Promoter
Murilo T. D. Bueno et al.
JOURNAL OF MOLECULAR BIOLOGY (2010)
Lens epithelium-derived growth factor fusion proteins redirect HIV-1 DNA integration
Andrea L. Ferris et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Crosstalk between sumoylation and acetylation regulates p53-dependent chromatin transcription and DNA binding
Shwu-Yuan Wu et al.
EMBO JOURNAL (2009)
Molecular Basis for SUMOylation-dependent Regulation of DNA Binding Activity of Heat Shock Factor 2
Yukihiro Tateishi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
SUMOylation and De-SUMOylation: Wrestling with Life's Processes
Edward T. H. Yeh
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
SUMO-Specific Protease 1 (SENP1) Reverses the Hormone-Augmented SUMOylation of Androgen Receptor and Modulates Gene Responses in Prostate Cancer Cells
Sanna Kaikkonen et al.
MOLECULAR ENDOCRINOLOGY (2009)
SMT3IP1, a nucleolar SUMO-specific protease, deconjugates SUMO-2 from nucleolar and cytoplasmic nucleophosmin
Tamotsu Nishida et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)
SUMO-modified Sp3 represses transcription by provoking local heterochromatic gene silencing
Bastian Stielow et al.
EMBO REPORTS (2008)
Sumoylation of specificity protein 1 augments its degradation by changing the localization and increasing the specificity protein 1 proteolytic process
Yi-Ting Wang et al.
JOURNAL OF MOLECULAR BIOLOGY (2008)
Concepts in sumoylation: a decade on
Ruth Geiss-Friedlander et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)
Sumoylation regulates diverse biological processes
J. Zhao
CELLULAR AND MOLECULAR LIFE SCIENCES (2007)
Differential interaction of HIV-1 integrase and JPO2 with the C terminus of LEDGF/p75
Koen Bartholomeeusen et al.
JOURNAL OF MOLECULAR BIOLOGY (2007)
SUMO and NF-κB ties
A. M. Mabb et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2007)
SUMO-specific proteases: a twist in the tail
Ronald Thomas Hay
TRENDS IN CELL BIOLOGY (2007)
Modification in reverse: the SUMO proteases
Debaditya Mukhopadhyay et al.
TRENDS IN BIOCHEMICAL SCIENCES (2007)
Lens epithelium-derived growth factor is an Hsp70-2 regulated guardian of lysosomal stability in human cancer
Mads Daugaard et al.
CANCER RESEARCH (2007)
Identification of the LEDGF/p75 binding site in HIV-1 integrase
Katrien Busschots et al.
JOURNAL OF MOLECULAR BIOLOGY (2007)
Overexpression of the lens epithelium-derived growth factor/p75 integrase binding domain inhibits human immunodeficiency virus replication
Jan De Rijck et al.
JOURNAL OF VIROLOGY (2006)
Sumoylated SnoN represses transcription in a promoter-specific manner
Ying-Han R. Hsu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Disruption of Ledgf/Psip1 results in perinatal mortality and homeotic skeletal transformations
Heidi G. Sutherland et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
Transcriptional co-activator p75 binds and tethers the Myc-interacting protein JPO2 to chromatin
Goedele N. Maertens et al.
JOURNAL OF CELL SCIENCE (2006)
Sumoylation inhibits cleavage of Sp1 N-terminal negative regulatory domain and inhibits Sp1-dependent transcription
ML Spengler et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Regulation of SUMOylation by reversible oxidation of SUMO conjugating enzymes
G Bossis et al.
MOLECULAR CELL (2006)
Regulation of heavy subunit chain of γ-glutamylcysteine synthetase by tumor necrosis factor-α in lens epithelial cells:: role of LEDGF/p75
Y Takamura et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2006)
DNA binding domains and nuclear localization signal of LEDGF: Contribution of two helix-turn-helix (HTH)like domains and a stretch of 58 amino acids of the N-terminal to the trans-activation potential of LEDGF
DP Singh et al.
JOURNAL OF MOLECULAR BIOLOGY (2006)
Comparison of the SUMO1 and ubiquitin conjugation pathways during the inhibition of proteasome activity with evidence of SUMO1 recycling
D Bailey et al.
BIOCHEMICAL JOURNAL (2005)
Upregulation of heat shock protein expression by proteasome inhibition: An antiapoptotic mechanism in the lens
N Awasthi et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2005)
Solution structure of the HIV-1 integrase-binding domain in LEDGF/p75
P Cherepanov et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2005)
Identification of the LEDGF/p75 HIV-1 integrase-interaction domain and NLS reveals NLS-independent chromatin tethering
M Vanegas et al.
JOURNAL OF CELL SCIENCE (2005)
Differential regulation of c-Jun-dependent transcription by SUMO-specific proteases
JK Cheng et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
SUMO: A history of modification
RT Hay
MOLECULAR CELL (2005)
Structures of the SUMO E1 provide mechanistic insights into SUMO activation and E2 recruitment to E1
LM Lois et al.
EMBO JOURNAL (2005)
Role for SUMO modification in facilitating transcriptional repression by BKLF
J Perdomo et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
Antinuclear autoantibodies in prostate cancer: Immunity to LEDGF/p75, a survival protein highly expressed in prostate tumors and cleaved during apoptosis
T Daniels et al.
PROSTATE (2005)
SUMO:: a regulator of gene expression and genome integrity
S Müller et al.
ONCOGENE (2004)
Characterization of the localization and proteolytic activity of the SUMO-specific protease, SENP1
D Bailey et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
SUMO and ubiquitin in the nucleus: different functions, similar mechanisms?
G Gill
GENES & DEVELOPMENT (2004)
Repression of the transactivating capacity of the oncoprotein PLAG1 by SUMOylation
F Van Dyck et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
LEDGF regulation of alcohol and aldehyde dehydrogenases in lens epithelial cells: stimulation of retinoic acid production and protection from ethanol toxicity
N Fatma et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2004)
Global shifts in protein sumoylation in response to electrophile and oxidative stress
LL Manza et al.
CHEMICAL RESEARCH IN TOXICOLOGY (2004)
Lens epithelium-derived growth factor (LEDGF/p75) expression in fetal and adult human
LT Chylack et al.
EXPERIMENTAL EYE RESEARCH (2004)
Identification of an evolutionarily conserved domain in human lens epithelium-derived growth factor/transcriptional co-activator p75 (LEDGF/p75) that binds HIV-1 integrase
P Cherepanov et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
SENP1 enhances androgen receptor-dependent transcription through desumoylation of histone deacetylase 1
JK Cheng et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Autoantibodies to DFS70/LEDGF are increased in alopecia areata patients
M Okamoto et al.
JOURNAL OF AUTOIMMUNITY (2004)
Protein modification by SUMO
ES Johnson
ANNUAL REVIEW OF BIOCHEMISTRY (2004)
Direct and distinguishable inhibitory roles for SUMO isoforms in the control of transcriptional synergy
S Holmstrom et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Nuclear and unclear functions of SUMO
JS Seeler et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2003)
LEDGE/p75: a novel nuclear autoantigen at the crossroads of cell survival and apoptosis
V Ganapathy et al.
AUTOIMMUNITY REVIEWS (2003)
Lens epithelium-derived growth factor relieves transforming growth factor-β1-induced transcription repression of heat shock proteins in human lens epithelial cells
P Sharma et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
LEDGF activation of PKC γ and gap junction disassembly in lens epithelial cells
TA Nguyen et al.
EXPERIMENTAL EYE RESEARCH (2003)
Post-translational modification by the small ubiquitin-related modifier SUMO has big effects on transcription factor activity
G Gill
CURRENT OPINION IN GENETICS & DEVELOPMENT (2003)
p300 transcriptional repression is mediated by SUMO modification
D Girdwood et al.
MOLECULAR CELL (2003)
Modification with SUMO - A role in transcriptional regulation
A Verger et al.
EMBO REPORTS (2003)
Regulating the regulators: Lysine modifications make their mark
RN Freiman et al.
CELL (2003)
HIV-1 integrase forms stable tetramers and associates with LEDGF/p75 protein in human cells
P Cherepanov et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
SUMO-1 protease-1 regulates gene transcription through PML
JL Best et al.
MOLECULAR CELL (2002)
The family of hepatoma-derived growth factor proteins: characterization of a new member HRP-4 and classification of its subfamilies
F Dietz et al.
BIOCHEMICAL JOURNAL (2002)
Detection of cytotoxic anti-LEDGF autoantibodies in atopic dermatitis
M Ayaki et al.
AUTOIMMUNITY (2002)
Association of the human SUMO-1 protease SENP2 with the nuclear pore
J Hang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
LEDGF, a survival factor, activates stress-related genes
T Shinohara et al.
PROGRESS IN RETINAL AND EYE RESEARCH (2002)
Covalent attachment of the SUMO-1 protein to the negative regulatory domain of the c-Myb transcription factor modifies its stability and transactivation capacity
J Bies et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Transcriptional regulation of the antioxidant protein 2 gene, a thiol-specific antioxidant, by lens epithelium-derived growth factor to protect cells from oxidative stress
N Fatma et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Regulation of heat shock transcription factor 1 by stress-induced SUMO-1 modification
YL Hong et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Polymeric chains of SUMO-2 and SUMO-3 are conjugated to protein substrates by SAE1/SAE2 and Ubc9
MH Tatham et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Spatial and temporal dynamics of two alternatively spliced regulatory factors, lens epithelium-derived growth factor (ledgf/p75) and p52, in the nucleus
Y Nishizawa et al.
CELL AND TISSUE RESEARCH (2001)
SUMO-1 modification regulates the DNA binding activity of heat shock transcription factor 2, a promyelocytic leukemia nuclear body associated transcription factor
ML Goodson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
LEDGF binds to heat shock and stress-related element to activate the expression of stress-related genes
DP Singh et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2001)
Sumo, ubiquitin's mysterious cousin
S Müller et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2001)
Regulation of p53 activity in nuclear bodies by a specific PML isoform
V Fogal et al.
EMBO JOURNAL (2000)
The PWWP domain: a potential protein-protein interaction domain in nuclear proteins influencing differentiation?
I Stec et al.
FEBS LETTERS (2000)
Functional heterogeneity of small ubiquitin-related protein modifiers SUMO-1 versus SUMO-2/3
H Saitoh et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Lens epithelium-derived growth factor (LEDGF/p75) and p52 are derived from a single gene by alternative splicing
DP Singh et al.
GENE (2000)