Related references
Note: Only part of the references are listed.QSAR analysis of pyrazolidine-3,5-diones derivatives as Dyrk1A inhibitors
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BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2009)
DYRK1A interacts with the REST/NRSF-SWI/SNF chromatin remodelling complex to deregulate gene clusters involved in the neuronal phenotypic traits of Down syndrome
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DYRK1A phosphorylates caspase 9 at an inhibitory site and is potently inhibited in human cells by harmine
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FEBS JOURNAL (2008)
Dual-specificity tyrosine(Y)-phosphorylation regulated kinase 1A-mediated phosphorylation of amyloid precursor protein: evidence for a functional link between Down syndrome and Alzheimer's disease
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THE DOWN SYNDROME CANDIDATE DUAL-SPECIFICITY TYROSINE PHOSPHORYLATION-REGULATED KINASE 1A PHOSPHORYLATES THE NEURODEGENERATION-RELATED SEPTIN 4
J. H. Sitz et al.
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The selectivity of protein kinase inhibitors: a further update
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DYRK1A-mediated hyperphosphorylation of Tau - A functional link between Down syndrome and Alzheimer disease
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Dyrk1A overexpression in immortalized hippocampal cells produces the neuropathological features of Down syndrome
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Dual-specificity tyrosine phosphorylation-regulated kinase 1A does not require tyrosine phosphorylation for activity in vitro
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The small molecule harmine is an antidiabetic cell-type-specific regulator of PPARγ expression
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DYRK1A (dual-specificity tyrosine-phosphorylated and -regulated kinase 1A):: A gene with dosage effect during development and neurogenesis
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THESCIENTIFICWORLDJOURNAL (2006)
Dyrk1A phosphorylates α-synuclein and enhances intracellular inclusion formation
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Putative therapeutic agents for the learning and memory deficits of people with Down syndrome
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NFAT dysregulation by increased dosage of DSCR1 and DYRK1A on chromosome 21
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Constitutive Dyrk1A is abnormally expressed in Alzheimer disease, Down syndrome, Pick disease, and related transgenic models
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NEUROBIOLOGY OF DISEASE (2005)
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R Benavides-Piccione et al.
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DYRK1A enhances the mitogen-activated protein kinase cascade in PC12 cells by forming a complex with Ras, B-Raf, and MEK1
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Protein synthesis by pure translation systems
Y Shimizu et al.
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Activation-loop autophosphorylation is mediated by a novel transitional intermediate form of DYRKs
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CELL (2005)
Specific inhibition of cyclin-dependent kinases and cell proliferation by harmine
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BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2004)
Transgenic mouse in vivo library of human down syndrome critical region 1:: Association between DYRK1A overexpression, brain development abnormalities, and cell cycle protein alteration
I Branchi et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2004)
dDYRK2:: a novel dual-specificity tyrosine-phosphorylation-regulated kinase in Drosophila
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BIOCHEMICAL JOURNAL (2003)
Expression patterns and subcellular localization of the Down syndrome candidate protein MNB/DYRK1A suggest a role in late neuronal differentiation
B Hämmerle et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2003)
The specificities of protein kinase inhibitors: an update
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Identification of the autophosphorylation sites and characterization of their effects in the protein kinase DYRK1A
S Himpel et al.
BIOCHEMICAL JOURNAL (2001)
Protein kinase Dyrk1 activates cAMP response element-binding protein during neuronal differentiation in hippocampal progenitor cells
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JOURNAL OF BIOLOGICAL CHEMISTRY (2001)