4.6 Article

Active γ-secretase is localized to detergent-resistant membranes in human brain

Related references

Note: Only part of the references are listed.
Article Biochemistry & Molecular Biology

Rat brain γ-secretase activity is highly influenced by detergents

Jenny Franberg et al.

BIOCHEMISTRY (2007)

Article Neurosciences

BACE1 interacts with lipid raft proteins.

Chinatsu Hattori et al.

JOURNAL OF NEUROSCIENCE RESEARCH (2006)

Review Biochemistry & Molecular Biology

The involvement of lipid rafts in Alzheimer's disease (Review)

JM Cordy et al.

MOLECULAR MEMBRANE BIOLOGY (2006)

Article Biochemistry & Molecular Biology

Spatial segregation of γ-secretase and substrates in distinct membrane domains

KS Vetrivel et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Article Multidisciplinary Sciences

CD147 is a regulatory subunit of the γ-secretase complex in Alzheimer's disease amyloid β-peptide production

SX Zhou et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)

Article Biochemistry & Molecular Biology

Association of active γ-secretase complex with lipid rafts

Y Urano et al.

JOURNAL OF LIPID RESEARCH (2005)

Article Biochemistry & Molecular Biology

Nanoscale organization of multiple GPI-anchored proteins in living cell membranes

P Sharma et al.

Article Cell Biology

Neuronal membrane cholesterol loss enhances amyloid pepticle generation

J Abad-Rodriguez et al.

JOURNAL OF CELL BIOLOGY (2004)

Article Biochemistry & Molecular Biology

The presenilin proteins are components of multiple membrane-bound complexes that have different biological activities

YJ Gu et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2004)

Review Neurosciences

The γ-secretase complex:: machinery for intramembrane proteolysis

T Iwatsubo

CURRENT OPINION IN NEUROBIOLOGY (2004)

Article Biochemistry & Molecular Biology

Association of γ-secretase with lipid rafts in post-golgi and endosome membranes

KS Vetrivel et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2004)

Article Biochemistry & Molecular Biology

Assembly of the γ-secretase complex involves early formation of an intermediate subcomplex of Aph-1 and nicastrin

MJ LaVoie et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)

Article Biochemistry & Molecular Biology

Partial purification and characterization of γ-secretase from post-mortem human brain

MR Farmery et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)

Article Multidisciplinary Sciences

γ-secretase is a membrane protein complex comprised of presenilin, nicastrin, aph-1, and pen-2

WT Kimberly et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)

Article Multidisciplinary Sciences

Resistance of cell membranes to different detergents

S Schuck et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)

Article Biochemistry & Molecular Biology

γ-Secretase activity is associated with a conformational change of Nicastrin

K Shirotani et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)

Article Cell Biology

Reconstitution of γ-secretase activity

D Edbauer et al.

NATURE CELL BIOLOGY (2003)

Article Multidisciplinary Sciences

The role of presenilin cofactors in the γ-secretase complex

N Takasugi et al.

NATURE (2003)

Article Neurosciences

Identity and function of gamma-secretase

WT Kimberly et al.

JOURNAL OF NEUROSCIENCE RESEARCH (2003)

Article Biochemistry & Molecular Biology

Amyloid-β oligomers:: their production, toxicity and therapeutic inhibition

DM Walsh et al.

BIOCHEMICAL SOCIETY TRANSACTIONS (2002)

Article Multidisciplinary Sciences

Presenilin and nicastrin regulate each other and determine amyloid β-peptide production via complex formation

D Edbauer et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)

Article Multidisciplinary Sciences

Presenilin, Notch, and the genesis and treatment of Alzheimer's disease

DJ Selkoe

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)

Article Biochemistry & Molecular Biology

Distinct intramembrane cleavage of the β-amyloid precursor protein family resembling γ-secretase-like cleavage of Notch

YJ Gu et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2001)

Article Multidisciplinary Sciences

Presenilin 1 is linked with γ-secretase activity in the detergent solubilized state

YM Li et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)

Article Medicine, General & Internal

Correlation between elevated levels of amyloid β-peptide in the brain and cognitive decline

J Näslund et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2000)