4.6 Article

Investigation of leucine-rich repeat kinase 2

Related references

Note: Only part of the references are listed.
Article Biochemistry & Molecular Biology

Phosphorylation of 4E-BP by LRRK2 affects the maintenance of dopaminergic neurons in Drosophila

Yuzuru Imai et al.

EMBO JOURNAL (2008)

Article Biochemistry & Molecular Biology

The Parkinson disease-associated leucine-rich repeat kinase 2 (LRRK2) is a dimer that undergoes intramolecular autophosphorylation

Elisa Greggio et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2008)

Article Biochemistry & Molecular Biology

Role of autophagy in G2019S-LRRK2-associated neurite shortening in differentiated SH-SY5Y cells

Edward D. Plowey et al.

JOURNAL OF NEUROCHEMISTRY (2008)

Article Neurosciences

The Roc domain of leucine-rich repeat kinase 2 is sufficient for interaction with microtubules

Payal N. Gandhi et al.

JOURNAL OF NEUROSCIENCE RESEARCH (2008)

Article Neurosciences

A study of LRRK2 mutations and Parkinson's disease in Brazil

Marcia Mattos Goncalves Pimentel et al.

NEUROSCIENCE LETTERS (2008)

Article Biochemistry & Molecular Biology

Mutations in LRRK2 as a cause of Parkinson's disease

Benoit I. Giasson et al.

NEUROSIGNALS (2008)

Article Biochemistry & Molecular Biology

Mechanistic insight into the dominant mode of the Parkinson's disease-associated G2019S LRRK2 mutation

Berta Luzon-Toro et al.

HUMAN MOLECULAR GENETICS (2007)

Article Biochemistry & Molecular Biology

LRRK2 phosphorylates moesin at threonine-558: characterization of how Parkinson's disease mutants affect kinase activity

Mahaboobi Jaleel et al.

BIOCHEMICAL JOURNAL (2007)

Article Biochemistry & Molecular Biology

Parkinson's disease-associated mutations in LRRK2 link enhanced GTP-binding and kinase activities to neuronal toxicity

Andrew B. West et al.

HUMAN MOLECULAR GENETICS (2007)

Article Neurosciences

Kinase activity of mutant LRRK2 mediates neuronal toxicity

Wanli W. Smith et al.

NATURE NEUROSCIENCE (2006)

Article Neurosciences

Kinase activity is required for the toxic effects of mutant LRRK2/dardarin

Elisa Greggio et al.

NEUROBIOLOGY OF DISEASE (2006)

Review Neurosciences

LRRK2 in Parkinson's disease: protein domains and functional insights

Ignacio F. Mata et al.

TRENDS IN NEUROSCIENCES (2006)

Article Biochemistry & Molecular Biology

Autophosphorylation of FGFR1 kinase is mediated by a sequential and precisely ordered reaction

CM Furdui et al.

MOLECULAR CELL (2006)

Article Biochemistry & Molecular Biology

The Parkinson disease causing LRRK2 mutation I2020T is associated with increased kinase activity

CJ Gloeckner et al.

HUMAN MOLECULAR GENETICS (2006)

Article Multidisciplinary Sciences

Leucine-rich repeat kinase 2 (LRRK2) interacts with parkin, and mutant LRRK2 induces neuronal degeneration

WW Smith et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)

Article Multidisciplinary Sciences

Parkinson's disease-associated mutations in leucine-rich repeat kinase 2 augment kinase activity

AB West et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)

Article Biochemical Research Methods

Expression, purification, and inhibition of human RET tyrosine kinase

L Mologni et al.

PROTEIN EXPRESSION AND PURIFICATION (2005)

Article Biochemistry & Molecular Biology

Autophosphorylation kinetics of protein kinases

ZX Wang et al.

BIOCHEMICAL JOURNAL (2002)

Article Multidisciplinary Sciences

The protein kinase complement of the human genome

G Manning et al.

SCIENCE (2002)