Related references
Note: Only part of the references are listed.Omi/HtrA2 is a positive regulator of autophagy that facilitates the degradation of mutant proteins involved in neurodegenerative diseases
B. Li et al.
CELL DEATH AND DIFFERENTIATION (2010)
The mitochondrial serine protease HtrA2/Omi cleaves RIP1 during apoptosis of Ba/F3 cells induced by growth factor withdrawal
Lieselotte Vande Walle et al.
CELL RESEARCH (2010)
Modulation of mitochondrial function and morphology by interaction of Omi/HtrA2 with the mitochondrial fusion factor OPA1
Nicole Kieper et al.
EXPERIMENTAL CELL RESEARCH (2010)
Association of Omi/HtrA2 with γ-secretase in mitochondria
Homira Behbahani et al.
NEUROCHEMISTRY INTERNATIONAL (2010)
Localization of HtrA2/Omi immunoreactivity in brains affected by Alzheimer's disease
Yasuhiro Kawamoto et al.
NEUROREPORT (2010)
A New Function of Human HtrA2 as an Amyloid-beta Oligomerization Inhibitor
Joel Kooistra et al.
JOURNAL OF ALZHEIMERS DISEASE (2009)
Mitochondrial quality control: insights on how Parkinson's disease related genes PINK1, parkin, and Omi/HtrA2 interact to maintain mitochondrial homeostasis
Ruben K. Dagda et al.
JOURNAL OF BIOENERGETICS AND BIOMEMBRANES (2009)
Omi is a mammalian heat-shock protein that selectively binds and detoxifies oligomeric amyloid-β
Meng-Lu Liu et al.
JOURNAL OF CELL SCIENCE (2009)
Neprilysin and Insulin-Degrading Enzyme Levels Are Increased in Alzheimer Disease in Relation to Disease Severity
James Scott Miners et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2009)
The mitochondrial serine protease HtrA2/Omi: an overview
L. Vande Walle et al.
CELL DEATH AND DIFFERENTIATION (2008)
Sequencing analysis of OMI/HTRA2 shows previously reported pathogenic mutations in neurologically normal controls
Javier Simon-Sanchez et al.
HUMAN MOLECULAR GENETICS (2008)
Genetic variability in the mitochondrial serine protease HTRA2 contributes to risk for Parkinson disease
Veerle Bogaerts et al.
HUMAN MUTATION (2008)
Genetic variation of Omi/HtrA2 and Parkinson's disease
Owen A. Ross et al.
PARKINSONISM & RELATED DISORDERS (2008)
The mitochondrial protease HtrA2 is regulated by Parkinson's disease-associated kinase PINK1
Helene Plun-Favreau et al.
NATURE CELL BIOLOGY (2007)
HtrA2 regulates β-amyloid precursor protein (APP) metabolism through endoplasmic reticulum-associated degradation
Henri J. Huttunen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
DJ-1 and UCH-L1 gene activity patterns in the brains of controls, Parkinson and schizophrenia patients and in rodents
Dagmar Galter et al.
PHYSIOLOGY & BEHAVIOR (2007)
Association study of two genetic variants in mitochondrial transcription factor A (TFAM) in Alzheimer's and Parkinson's disease
Andrea Carmine Belin et al.
NEUROSCIENCE LETTERS (2007)
Decreased expression and activity of neprilysin in Alzheimer disease are associated with cerebral amyloid angiopathy
James Scott Miners et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2006)
Loss of function mutations in the gene encoding Omi/HtrA2 in Parkinson's disease
KM Strauss et al.
HUMAN MOLECULAR GENETICS (2005)
Alzheimer's disease-associated amyloid beta interacts with the human serme protease HtrA2/Omi
HJ Park et al.
NEUROSCIENCE LETTERS (2004)
Autocatalytic processing of HtrA2/Omi is essential for induction of caspase-dependent cell death through antagonizing XIAP
YM Seong et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
The C-terminal tail of presenilin regulates Omi/HtrA2 protease activity
S Gupta et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Binding specificity and regulation of the serine protease and PDZ domains of HtrA2/Omi
LM Martins et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
ALDH1 mRNA: presence in human dopamine neurons and decreases in substantia nigra in Parkinson's disease and in the ventral tegmental area in schizophrenia
D Galter et al.
NEUROBIOLOGY OF DISEASE (2003)
Loss of Omi mitochondrial protease activity causes the neuromuscular disorder of mnd2 mutant mice
JM Jones et al.
NATURE (2003)
Declining expression of neprilysin in Alzheimer disease vasculature: Possible involvement in cerebral amyloid angiopathy
M Carpentier et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2002)
Identification of Omi/HtrA-2 as a mitochondrial apoptotic serine protease that disrupts inhibitor of apoptosis protein-caspase interaction
R Hegde et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
The serine protease Omi/HtrA2 regulates apoptosis by binding XIAP through a reaper-like motif
LM Martins et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
HtrA2 promotes cell death through its serine protease activity and its ability to antagonize inhibitor of apoptosis proteins
AM Verhagen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death
Y Suzuki et al.
MOLECULAR CELL (2001)
Characterization of human HtrA2, a novel serine protease involved in the mammalian cellular stress response
CW Gray et al.
EUROPEAN JOURNAL OF BIOCHEMISTRY (2000)