4.7 Article

Altered enzymatic activity and allele frequency of OMI/HTRA2 in Alzheimer's disease

Related references

Note: Only part of the references are listed.
Article Biochemistry & Molecular Biology

Association of Omi/HtrA2 with γ-secretase in mitochondria

Homira Behbahani et al.

NEUROCHEMISTRY INTERNATIONAL (2010)

Article Neurosciences

A New Function of Human HtrA2 as an Amyloid-beta Oligomerization Inhibitor

Joel Kooistra et al.

JOURNAL OF ALZHEIMERS DISEASE (2009)

Article Clinical Neurology

Neprilysin and Insulin-Degrading Enzyme Levels Are Increased in Alzheimer Disease in Relation to Disease Severity

James Scott Miners et al.

JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2009)

Review Biochemistry & Molecular Biology

The mitochondrial serine protease HtrA2/Omi: an overview

L. Vande Walle et al.

CELL DEATH AND DIFFERENTIATION (2008)

Article Biochemistry & Molecular Biology

Sequencing analysis of OMI/HTRA2 shows previously reported pathogenic mutations in neurologically normal controls

Javier Simon-Sanchez et al.

HUMAN MOLECULAR GENETICS (2008)

Article Clinical Neurology

Genetic variation of Omi/HtrA2 and Parkinson's disease

Owen A. Ross et al.

PARKINSONISM & RELATED DISORDERS (2008)

Article Cell Biology

The mitochondrial protease HtrA2 is regulated by Parkinson's disease-associated kinase PINK1

Helene Plun-Favreau et al.

NATURE CELL BIOLOGY (2007)

Article Biochemistry & Molecular Biology

HtrA2 regulates β-amyloid precursor protein (APP) metabolism through endoplasmic reticulum-associated degradation

Henri J. Huttunen et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Article Clinical Neurology

Decreased expression and activity of neprilysin in Alzheimer disease are associated with cerebral amyloid angiopathy

James Scott Miners et al.

JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2006)

Article Biochemistry & Molecular Biology

Loss of function mutations in the gene encoding Omi/HtrA2 in Parkinson's disease

KM Strauss et al.

HUMAN MOLECULAR GENETICS (2005)

Article Biochemistry & Molecular Biology

Autocatalytic processing of HtrA2/Omi is essential for induction of caspase-dependent cell death through antagonizing XIAP

YM Seong et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2004)

Article Biochemistry & Molecular Biology

The C-terminal tail of presenilin regulates Omi/HtrA2 protease activity

S Gupta et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2004)

Article Biochemistry & Molecular Biology

Binding specificity and regulation of the serine protease and PDZ domains of HtrA2/Omi

LM Martins et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)

Article Clinical Neurology

Declining expression of neprilysin in Alzheimer disease vasculature: Possible involvement in cerebral amyloid angiopathy

M Carpentier et al.

JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2002)

Article Biochemistry & Molecular Biology

The serine protease Omi/HtrA2 regulates apoptosis by binding XIAP through a reaper-like motif

LM Martins et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2002)

Article Biochemistry & Molecular Biology

HtrA2 promotes cell death through its serine protease activity and its ability to antagonize inhibitor of apoptosis proteins

AM Verhagen et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2002)

Article Biochemistry & Molecular Biology

Characterization of human HtrA2, a novel serine protease involved in the mammalian cellular stress response

CW Gray et al.

EUROPEAN JOURNAL OF BIOCHEMISTRY (2000)