Journal
FARADAY DISCUSSIONS
Volume 137, Issue -, Pages 65-83Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/b702920a
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The authors present an approach for specific and rapid unlabeled detection of a virus by using a microsphere- based whispering gallery mode sensor that transduces the interaction of a whole virus with an anchored antibody. They show theoretically that this sensor can detect a single virion below the mass of HIV. A micro-fluidic device is presented that enables the discrimination between viruses of similar size and shape.
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