Journal
FACIAL PLASTIC SURGERY
Volume 26, Issue 5, Pages 385-395Publisher
THIEME MEDICAL PUBL INC
DOI: 10.1055/s-0030-1265017
Keywords
Mesenchymal stem cell; bone tissue engineering; allograft; periosteum; BMP-2
Categories
Ask authors/readers for more resources
Few areas of translational medicine carry as much excitement and hope as stem cell therapies. Because of recent advances in material science and stem cell and developmental biology that help to target molecules and pathways to restore the body's regenerative capacity, the engineering of missing tissue is quickly becoming a reality. Classically, tissue engineering has been thought to require external regenerative resources including a scaffold, cells, and growth factors. The allure of providing an exact replica of a missing bone that incorporates to become indistinguishable from self, has the capacity to heal and grow, is resistant to infection, and has minimal morbidity is a holy grail to all surgeons who work with bone. This article attempts to shed light on the use of stem cells for craniofacial reconstruction, including important principles learned from other scientific disciplines, relevant animal models for tissue engineering, early clinical reports from our experience and that of others, and future directions.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available