Endothelial keratoplasty in the management of irido-corneal endothelial syndrome

Purpose To describe the results of endothelial keratoplasty (EK) in the management of irido-corneal endothelial (ICE) syndrome. Design Retrospective, consecutive, interventional case series. Methods Eight eyes of seven patients underwent EK for corneal edema owing to ICE syndrome. Simultaneous cataract surgery was performed in five eyes. The charts were reviewed for demographics, clinical findings, and outcomes after EK. Results Mean age was 50.4 years (range 35-59 years). Mean follow-up was 12.5 months (range 6-24 months). Corneal clarity was restored in all eyes and was maintained till the last follow-up. Four patients had acute rise in the intraocular pressure in the post-operative period, which was well controlled on medical treatment. One patient who was non-compliant with medications and regular follow-up advice had progression of glaucomatous disc changes and visual field loss. The best-corrected visual acuity ranged from 20/50-20/30. Conclusions EK is a viable option in ICE syndrome. Adequate control of glaucoma is the paramount factor in maintaining good visual acuity in these eyes. Eye (2013) 27, 564-566; doi:10.1038/eye.2012.298; published online 25 January 2013