Journal
EYE
Volume 27, Issue 3, Pages 329-339Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/eye.2012.257
Keywords
review; keratoconus; crosslinking; intracorneal ring; intraocular lens; meta-analysis
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Funding
- UK National Institute for Health Research Biomedical Research Centre in Ophthalmology at Moorfields Eye Hospital
- UCL Institute of Ophthalmology
- MRC [G84/6715] Funding Source: UKRI
- Medical Research Council [G84/6715] Funding Source: researchfish
- National Institute for Health Research [CL-2009-18-007] Funding Source: researchfish
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Pre-2000, the clinical management of keratoconus centred on rigid contact lens fitting when spectacle corrected acuity was no longer adequate, and transplantation where contact lens wear failed. Over the last decade, outcome data have accumulated for new interventions including corneal collagen crosslinking, intracorneal ring implantation, topographic phototherapeutic keratectomy, and phakic intraocular lens implantation. We review the current evidence base for these interventions and their place in new management pathways for keratoconus under two key headings: corneal shape stabilisation and visual rehabilitation. Eye (2013) 27, 329-339; doi:10.1038/eye.2012.257; published online 21 December 2012
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