Journal
EYE
Volume 25, Issue 1, Pages 84-90Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/eye.2010.157
Keywords
choroideremia; cystic macular oedema; SD-OCT
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Funding
- Foundation Fighting Blindness, Owings Mills, Maryland
- Grant Healthcare Foundation, Lake Forest, Illinois
- NIH [EYO1792]
- Research to Prevent Blindness
- NATIONAL EYE INSTITUTE [P30EY001792] Funding Source: NIH RePORTER
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Purpose To determine the prevalence of cystic macular oedema (CME) in patients with choroideremia (CHM) by using spectral-domain optical coherence tomography (SD-OCT). Methods A total 16 patients affected with CHM were enroled in the study. All patients underwent a complete eye examination. SD-OCT was performed using an OPKO spectral-domain OCT/SLO instrument. Results The average age of the study patients was 44.0 +/- 16.0 years (range, 13-63 years). Out of the 16 patients with CHM, 10 patients (62.5%) showed a degree of CME on SD-OCT testing in at least one eye, and 8 patients (50%) showed CME in both eyes. Conclusions Because of its notable prevalence, it would seem prudent to screen CHM patients by SD-OCT for the possible presence of CME and to identify those amenable to future treatment strategies for their macular oedema. Eye (2011) 25, 84-90; doi: 10.1038/eye.2010.157; published online 22 October 2010
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