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PC Mahon et al.
GENES & DEVELOPMENT (2001)
C-elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation
ACR Epstein et al.
CELL (2001)
Hypoxia in human prostate carcinoma -: An Eppendorf Po2 study
B Movsas et al.
AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS (2001)
Independent function of two destruction domains in hypoxia-inducible factor-α chains activated by prolyl hydroxylation
N Masson et al.
EMBO JOURNAL (2001)
HIF-1α binding to VHL is regulated by stimulus-sensitive proline hydroxylation
F Yu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
HER2 (neu) signaling increases the rate of hypoxia-inducible factor 1α (HIF-1α) synthesis:: Novel mechanism for HIF-1-mediated vascular endothelial growth factor expression
E Laughner et al.
MOLECULAR AND CELLULAR BIOLOGY (2001)
HIFα targeted for VHL-mediated destruction by proline hydroxylation:: Implications for O2 sensing
M Ivan et al.
SCIENCE (2001)
Targeting of HIF-α to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation
P Jaakkola et al.
SCIENCE (2001)
Levels of hypoxia-inducible factor-1α during breast carcinogenesis
R Bos et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2001)
Tumor hypoxia:: Definitions and current clinical, biologic, and molecular aspects
M Höckel et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2001)
Suppression of tumor growth through disruption of hypoxia-inducible transcription
AL Kung et al.
NATURE MEDICINE (2000)
Up-regulation of hypoxia-inducible factors HIF-1α and HIF-2α under normoxic conditions in renal carcinoma cells by von Hippel-Lindau tumor suppressor gene loss of function
M Krieg et al.
ONCOGENE (2000)
Induction of hypoxia-inducible-factor 1 by nitric oxide is mediated via the PI3K pathway
KB Sandau et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2000)
The expression and distribution of the hypoxia-inducible factors HIF-1α and HIF-2α in normal human tissues, cancers, and tumor-associated macrophages
KL Talks et al.
AMERICAN JOURNAL OF PATHOLOGY (2000)
p53 checkpoint-defective cells are sensitive to X rays, but not hypoxia
NC Denko et al.
EXPERIMENTAL CELL RESEARCH (2000)
MAP kinases and hypoxia in the control of VEGF expression
E Berra et al.
CANCER AND METASTASIS REVIEWS (2000)