4.4 Review

Chitosan-based systems for the delivery of vaccine antigens

Journal

EXPERT REVIEW OF VACCINES
Volume 8, Issue 7, Pages 937-953

Publisher

TAYLOR & FRANCIS LTD
DOI: 10.1586/ERV.09.47

Keywords

chitosan; chitosan derivative; mucosal vaccination; nasal; vaccine delivery; veterinary

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This review discusses the current status of chitosan and its derivatives as adjuvants and delivery systems in vaccine delivery, and their future possibilities and challenges. After a brief introduction to adjuvants and delivery systems, chitosan will be described in detail in regard to vaccine formulation. Applications of chitosan and its derivatives will be reviewed and their proposed mechanisms in the enhancement of immune responses will be discussed.

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