Journal
EXPERT REVIEW OF MOLECULAR DIAGNOSTICS
Volume 13, Issue 2, Pages 183-204Publisher
TAYLOR & FRANCIS AS
DOI: 10.1586/ERM.12.134
Keywords
autoimmune diseases; biomarkers; cancer; cardiovascular diseases; infectious diseases; miRNAs; molecular diagnostics; neurological diseases; noncoding RNAs
Categories
Funding
- Henri Benedictus Fund/Belgian American Education Foundation
- Fulbright Association
- Belgian American Education Foundation
- University of Texas MD Anderson Research Trust
- University of Texas System Regents Research Scholar
- CLL Global Research Foundation
- NIH/NCI [CA135444]
- Department of Defense Breast Cancer Idea Award
- Developmental Research Awards in Breast Cancer, Ovarian Cancer, Brain Cancer, Prostate Cancer, Multiple Myeloma, Leukemia [P50 CA100632]
- Developmental Research Awards in Head and Neck [P50 CA097007]
- SPOREs, a SINF MDACC_DKFZ grant in CLL
- Laura and John Arnold Foundation
- RGK Foundation
- Estate of CG Johnson Jr.
Ask authors/readers for more resources
Noncoding RNAs (ncRNAs) are transcripts that have no apparent protein-coding capacity; however, many ncRNAs have been found to play a major biological role in human physiology. Their deregulation is implicated in many human diseases, but their exact roles are only beginning to be elucidated. Nevertheless, ncRNAs are extensively studied as a novel source of biomarkers, and the fact that they can be detected in body fluids makes them extremely suitable for this purpose. The authors mainly focus on ncRNAs as biomarkers in cancer, but also touch on other human diseases such as cardiovascular diseases, autoimmune diseases, neurological disorders and infectious diseases. The authors discuss the established methods and provide a selection of emerging new techniques that can be used to detect and quantify ncRNAs. Finally, the authors discuss ncRNAs as a new strategy for therapeutic interventions.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available