Journal
EXPERT REVIEW OF MEDICAL DEVICES
Volume 7, Issue 3, Pages 343-356Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1586/ERD.10.14
Keywords
ablation; laser; MAPLE direct write; medical; rapid prototyping; selective laser sintering; stereolithography; two-photon polymerization
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Funding
- National Science Foundation [0936110]
- Department of Defense
- National Institutes of Health
- NATIONAL INSTITUTE ON DRUG ABUSE [R21DA026980] Funding Source: NIH RePORTER
- Office Of The Director [0936110] Funding Source: National Science Foundation
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Laser-based direct writing of materials has undergone significant development in recent years. The ability to modify a variety of materials at small length scales and using short production times provides laser direct writing with unique capabilities for fabrication of medical devices. In many laser-based rapid prototyping methods, microscale and submicroscale structuring of materials is controlled by computer-generated models. Various laser-based direct write methods, including selective laser sintering/melting, laser machining, matrix-assisted pulsed-laser evaporation direct write, stereolithography and two-photon polymerization, are described. Their use in fabrication of microstructured and nanostructured medical devices is discussed. Laser direct writing may be used for processing a wide variety of advanced medical devices, including patient-specific prostheses, drug delivery devices, biosensors, stents and tissue-engineering scaffolds.
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